Moku virus; a new Iflavirus found in wasps, honey bees and Varroa.

Moku virus; a new Iflavirus found in wasps, honey bees and Varroa.
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DOI:
10.1038/srep34983
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发表时间:
2016-10-07
期刊:
影响因子:
4.6
通讯作者:
Schroeder DC
Schroeder DC
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Mordecai GJ;Brettell LE;Pachori P;Villalobos EM;Martin SJ;Jones IM;Schroeder DC

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全球新发传染病 (EID) 呈上升趋势,影响包括蜜蜂在内的多种物种。由瓦螨传播驱动的单链 RNA 变形翅病毒 (DWV) 在全球的流行已得到充分记录。然而,DWV 只是感染广泛宿主的众多昆虫 RNA 病毒之一。在这里,我们报告了一种名为 Moku 病毒 (MV) 的新型 ifflavirus 的完整基因组序列,该病毒是在夏威夷收集的社会黄蜂 Vespula pensylvanica 中发现的。新基因组长 10,056 个核苷酸,编码 3050 个氨基酸的多蛋白。系统发育分析表明,MV 与慢蜂麻痹病毒 (SBPV) 关系最密切,该病毒对蜜蜂具有高毒力,但很少检测到。令人担忧的是,在同一地点的蜜蜂和瓦螨中也检测到了 MV 序列,这表明 MV 还可以感染其他膜翅目昆虫和螨虫宿主。
There is an increasing global trend of emerging infectious diseases (EIDs) affecting a wide range of species, including honey bees. The global epidemic of the single stranded RNA Deformed wing virus (DWV), driven by the spread of Varroa destructor has been well documented. However, DWV is just one of many insect RNA viruses which infect a wide range of hosts. Here we report the full genome sequence of a novel Iflavirus named Moku virus (MV), discovered in the social wasp Vespula pensylvanica collected in Hawaii. The novel genome is 10,056 nucleotides long and encodes a polyprotein of 3050 amino acids. Phylogenetic analysis showed that MV is most closely related to Slow bee paralysis virus (SBPV), which is highly virulent in honey bees but rarely detected. Worryingly, MV sequences were also detected in honey bees and Varroa from the same location, suggesting that MV can also infect other hymenopteran and Acari hosts.
新兴的病毒基因型的毒力升高是蜜蜂丧失的驱动力。
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