Real-time catheter-directed MRA with effective background suppression and persistent rendering.
Real-time catheter-directed MRA with effective background suppression and persistent rendering.
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DOI：
10.1002/jmri.21409
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发表时间：
2008-08
影响因子：
4.4
通讯作者：
McVeigh, Elliot R.
中科院分区：
文献类型：
--
作者：
Guttman, Michael A.;Raval, Amish N.;Lederman, Robert J.;McVeigh, Elliot R.
开发一种实时磁共振血管造影 (rt-MRA) 成像和可视化技术，与临床 MR 扫描仪上的实时交互式成像环境完全集成。采用动脉内注射造影剂和成像处理技术来快速导管引导评估血管通畅性和区域组织灌注。操作员可以对多个薄片进行成像，以最大化解剖细节，或使用厚切片或投影成像来最大化血管覆盖范围。采用脉冲序列和图像处理技术来确保背景抑制。最大像素值的累积允许在推注信号穿过血管并进入组织时持续显示推注信号。使用自动亮度调节来确保丸剂通过的所有阶段的可见度。冠状动脉、肾动脉和颈动脉的实验性动脉内 rtMRA 表明，猪的血管轨迹和灌注区域清晰可见。在手术过程中无需停止扫描仪即可轻松在注射造影剂后在标准实时成像和 rtMRA 成像之间进行切换。所提出的技术有助于使用实时 MRI 实现动脉内造影剂注射的可视化。尽管该技术设计用于在 rtMRI 引导的介入手术期间快速部署，但该技术也可用于补充血管解剖、血流或灌注的研究。
To develop an imaging and visualization technique for real-time magnetic resonance angiography (rt-MRA) fully integrated with a real-time interactive imaging environment on a clinical MR scanner. Intraarterial injections of contrast agent and imaging processing techniques were employed for rapid catheter-directed assessment of vessel patency and regional tissue perfusion. Operators can image multiple thin slices to maximize anatomic detail or use thick slice or projection imaging to maximize vessel coverage. Techniques in both pulse sequence and image processing were employed to ensure background suppression. Accumulation of maximum pixel values allows persistent display of bolus signal as it passes through the vessels and into tissues. Automatic brightness adjustment was used to ensure visibility at all stages of bolus passage. Experimental intraarterial rtMRA of coronary, renal, and carotid arteries show that vessel trajectories and perfusion territories are well visualized in swine. Switching between standard real-time imaging and rtMRA imaging after contrast injection was easy to perform during a procedure without stopping the scanner. The proposed technique facilitates visualization of intraarterial contrast injections using real-time MRI. Although designed for rapid deployment during rtMRI-guided interventional procedures, the technique may also be useful to supplement the study of vessel anatomy, flow, or perfusion.
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影响因子：
6.4
作者：
Guttman, MA;Lederman, RJ;McVeigh, ER
通讯作者：
McVeigh, ER
影响因子：
4.4
作者：
Gui, Dawei;Tsekos, Nikolaos V.
通讯作者：
Tsekos, Nikolaos V.
影响因子：
4.4
作者：
Tsekos, NV;Woodard, PK;Gropler, RJ
通讯作者：
Gropler, RJ
影响因子：
3.3
作者：
Wang, Y;Johnston, DL;Ehman, RL
通讯作者：
Ehman, RL
影响因子：
19.7
作者：
Green, JD;Omary, RA;Li, DB
通讯作者：
Li, DB