Soy and Health Update: Evaluation of the Clinical and Epidemiologic Literature.
Soy and Health Update: Evaluation of the Clinical and Epidemiologic Literature.
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DOI：
10.3390/nu8120754
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发表时间：
2016-11-24
期刊：
影响因子：
5.9
通讯作者：
Messina M
中科院分区：
文献类型：
--
作者：
Messina M
长期以来，素食一直被认为是优质蛋白质和健康脂肪的来源，但在过去的25年里，这些食物在慢性病预防和治疗中的作用受到了严格的调查。例如，有证据表明，它们可以降低患冠心病、乳腺癌和前列腺癌的风险。此外，大豆还能缓解潮热，并可能对肾功能产生有利影响，缓解抑郁症状，改善皮肤健康。人们对大豆食品的关注很大程度上是因为它们是大豆酮的丰富来源。异黄酮被分类为植物雌激素和选择性雌激素受体调节剂。尽管有许多建议的好处，但大豆酮的存在导致人们担心大豆可能会对某些人产生不良影响。然而，这些担忧主要基于动物研究，而人类研究支持大豆食品的安全性和益处。支持安全性的是欧洲食品安全局最近的结论，即对绝经后妇女的乳房、甲状腺或子宫没有不利影响。本综述涵盖了涉及大豆的主要研究领域，主要集中在临床和流行病学研究。还提供了亚洲大豆摄入量、大豆酮和营养成分的背景信息。
Soyfoods have long been recognized as sources of high-quality protein and healthful fat, but over the past 25 years these foods have been rigorously investigated for their role in chronic disease prevention and treatment. There is evidence, for example, that they reduce risk of coronary heart disease and breast and prostate cancer. In addition, soy alleviates hot flashes and may favorably affect renal function, alleviate depressive symptoms and improve skin health. Much of the focus on soyfoods is because they are uniquely-rich sources of isoflavones. Isoflavones are classified as both phytoestrogens and selective estrogen receptor modulators. Despite the many proposed benefits, the presence of isoflavones has led to concerns that soy may exert untoward effects in some individuals. However, these concerns are based primarily on animal studies, whereas the human research supports the safety and benefits of soyfoods. In support of safety is the recent conclusion of the European Food Safety Authority that isoflavones do not adversely affect the breast, thyroid or uterus of postmenopausal women. This review covers each of the major research areas involving soy focusing primarily on the clinical and epidemiologic research. Background information on Asian soy intake, isoflavones, and nutrient content is also provided.
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影响因子：
39
作者：
Avis, Nancy E.;Crawford, Sybil L.;Greendale, Gail;Bromberger, Joyce T.;Everson-Rose, Susan A.;Gold, Ellen B.;Hess, Rachel;Joffe, Hadine;Kravitz, Howard M.;Tepper, Ping G.;Thurston, Rebecca C.
通讯作者：
Thurston, Rebecca C.
影响因子：
4
作者：
Atteritano, M.;Mazzaferro, S.;Bagnato, G.
通讯作者：
Bagnato, G.
影响因子：
158.5
作者：
ANDERSON, JW;JOHNSTONE, BM;COOKNEWELL, ME
通讯作者：
COOKNEWELL, ME
DOI：
10.1097/gme.0000000000000280
发表时间：
2015-02
期刊：
Menopause (New York, N.Y.)
影响因子：
--
作者：
Alekel DL;Genschel U;Koehler KJ;Hofmann H;Van Loan MD;Beer BS;Hanson LN;Peterson CT;Kurzer MS
通讯作者：
Kurzer MS
影响因子：
3.3
作者：
Agostoni, Carlo;Bresson, Jean-Louis;Verhagen, Hans
通讯作者：
Verhagen, Hans