Principles and concepts of DNA replication in bacteria, archaea, and eukarya.
Principles and concepts of DNA replication in bacteria, archaea, and eukarya.
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DOI:
10.1101/cshperspect.a010108
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发表时间:
2013-07-01
影响因子:
7.2
通讯作者:
Stillman B
中科院分区:
文献类型:
--
作者:
O'Donnell M;Langston L;Stillman B
The accurate copying of genetic information in the double helix of DNA is essential for inheritance of traits that define the phenotype of cells and the organism. The core machineries that copy DNA are conserved in all three domains of life, bacteria, archaea and eukaryotes. This introductory chapter outlines the general nature of the DNA replication machinery, but also points out important and key differences. The most complex organisms, eukaryotes, have to coordinate the initiation of DNA replication from many origins in each genome and impose regulation that maintains genomic integrity, not only for the sake of each cell, but for the organism as a whole. In addition, DNA replication in eukaryotes needs to be coordinated with inheritance of chromatin, developmental patterning of tissues and with cell division to ensure that the genome replicates once per cell division cycle.
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DOI:
10.1098/rstb.2011.0073
发表时间:
2011-12-27
期刊:
Philosophical transactions of the Royal Society of London. Series B, Biological sciences
影响因子:
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作者:
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通讯作者:
Diffley JF
影响因子:
7.2
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影响因子:
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DOI:
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发表时间:
1989-01-01
影响因子:
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作者:
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通讯作者:
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影响因子:
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