Transmission of SARS-CoV-2 through breast milk and breastfeeding: a living systematic review.
Transmission of SARS-CoV-2 through breast milk and breastfeeding: a living systematic review.
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DOI：
10.1111/nyas.14477
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发表时间：
2021-01
影响因子：
5.2
通讯作者：
Mehta S
中科院分区：
文献类型：
--
作者：
Centeno-Tablante E;Medina-Rivera M;Finkelstein JL;Rayco-Solon P;Garcia-Casal MN;Rogers L;Ghezzi-Kopel K;Ridwan P;Peña-Rosas JP;Mehta S
2019年冠状病毒病大流行（COVID-19）是由一种新型冠状病毒株--严重急性呼吸系统综合征冠状病毒2（SARS-CoV-2）感染引起的。目前，关于母婴传染，特别是通过母乳和母乳喂养传染的可能性的信息有限。在这里，我们提供了一个活生生的系统性综述，以获取可能需要改变母乳和母乳喂养指导的信息，因为这一领域存在不确定性。我们的检索共检索到19，414条记录; 605条被认为具有全文资格，未发现正在进行的试验。我们的审查包括340份记录，37份有母乳样本，303份没有。37篇分析母乳样本的文章报告了77名母乳喂养子女的母亲;其中，77名儿童中有19名经RT-PCR检测确诊为COVID-19病例，包括14名新生儿和5名年龄较大的婴儿。在68份来自COVID-19母亲的分析母乳样本中，有9份对SARS-CoV-2 RNA呈阳性;在接触过COVID-19的婴儿中，有4份呈阳性，2份呈阴性。目前，没有证据表明SARS-CoV-2通过母乳传播。研究需要更长的随访期，以收集婴儿喂养方法和母乳中病毒存在的数据。本综述的目的是评估与SARS-CoV-2可能通过母乳和母乳喂养传播有关的现有证据（即，相关的体液，如血液、汗液和呼吸道飞沫）或飞沫传播，由于与婴儿或幼儿密切接触，通过皮肤接触或空气传播。该审查旨在支持政策制定者在持续流行的背景下制定基于证据的全球、区域和国家婴儿喂养指南。
The pandemic of coronavirus disease 2019 (COVID‐19) is caused by infection with a novel coronavirus strain, the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). At present, there is limited information on potential transmission of the infection from mother to child, particularly through breast milk and breastfeeding. Here, we provide a living systematic review to capture information that might necessitate changes in the guidance on breast milk and breastfeeding given the uncertainty in this area. Our search retrieved 19,414 total records; 605 were considered for full‐text eligibility and no ongoing trials were identified. Our review includes 340 records, 37 with breast milk samples and 303 without. The 37 articles with analyzed breast milk samples reported on 77 mothers who were breastfeeding their children; among them, 19 of 77 children were confirmed COVID‐19 cases based on RT‐PCR assays, including 14 neonates and five older infants. Nine of the 68 analyzed breast milk samples from mothers with COVID‐19 were positive for SARS‐CoV‐2 RNA; of the exposed infants, four were positive and two were negative for COVID‐19. Currently, there is no evidence of SARS‐CoV‐2 transmission through breast milk. Studies are needed with longer follow‐up periods that collect data on infant feeding practices and on viral presence in breast milk. The objective of this review is to assess available evidence related to the possible transmission of SARS‐ CoV‐2 through breast milk and through breastfeeding (i.e., related bodily fluids, such as blood, sweat, and respiratory droplets) or droplet transmission due to close contact with the infant or young child via skin‐to‐skin exposure or airborne transmission. The review aims to support policymakers in making evidence‐informed global, regional, and national guidelines on infant feeding in the context of the ongoing pandemic.
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DOI：
10.1016/j.ajogmf.2020.100118
发表时间：
2020-05-01
影响因子：
6.3
作者：
Breslin, Noelle;Baptiste, Caitlin;Goffman, Dena
通讯作者：
Goffman, Dena
影响因子：
7.2
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通讯作者：
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影响因子：
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影响因子：
--
作者：
Al-Kuraishy, Hayder M;Al-Maiahy, Thabat J;Ali, Zaid H
通讯作者：
Ali, Zaid H
影响因子：
7.2
作者：
Blauvelt, Christine A.;Chiu, Catherine;Gaw, Stephanie L.
通讯作者：
Gaw, Stephanie L.