What If Low Back Pain Is the Most Prevalent Parkinsonism in the World?

What If Low Back Pain Is the Most Prevalent Parkinsonism in the World?
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DOI:
10.3389/fneur.2018.00313
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发表时间:
2018
影响因子:
3.4
通讯作者:
Horak FB
Horak FB
中科院分区:
医学3区
文献类型:
--
作者:
Jacobs JV;Henry SM;Horak FB

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腰痛(LBP)的发病率接近10%,在全球疾病负担中排名最高,多年来一直处于残疾状态;帕金森氏病(PD)位列前100名,最严重的健康状况是失去多年的健康状况和多年来的残疾生活。最近的证据表明,患有慢性复发性LBP的人表现出许多姿势障碍,这让人想起帕金森病等神经姿势障碍。我们比较和对比与LBP和PD相关的姿势损害,以便为这两种情况的治疗策略提供信息。文献表明,LBP和PD都与本体感觉功能受损、站立平衡时的感觉定向、预期姿势调整、自动姿势反应和纹状体皮质功能受损有关。尽管LBP和PD的姿势损害在本质上是相似的,但LBP的姿势损害似乎比PD更具体。同样,尽管这两种健康状况都与纹状体皮质功能改变有关,但PD和LBP的神经结构或功能改变的性质不同。由于与PD相关的LBP的高患病率,对PD患者进行LBP的重点治疗可能会对他们的姿势障碍和残疾有所裨益。此外,LBP可能会受益于不仅仅是肌肉骨骼损伤;因此,临床医生应该考虑包括解决姿势运动控制障碍的方法。
Low back pain (LBP) has a point prevalence of nearly 10% and ranks highest in global disease burden for years lived with disability; Parkinson’s disease (PD) ranks in the top 100 most disabling health conditions for years lost and years lived with disability. Recent evidence suggests that people with chronic, recurrent LBP exhibit many postural impairments reminiscent of a neurological postural disorder such as PD. We compare and contrast postural impairments associated with LBP and PD in order to inform treatment strategies for both conditions. The literature suggests that both LBP and PD associate with impaired proprioceptive function, sensory orientation during standing balance, anticipatory postural adjustments, automatic postural responses, and striatal-cortical function. Although postural impairments are similar in nature for LBP and PD, the postural impairments with LBP appear more specific to the trunk than for PD. Likewise, although both health conditions associate with altered striatal-cortical function, the nature of the altered neural structure or function differ for PD and LBP. Due to the high prevalence of LBP associated with PD, focused treatment of LBP in people with PD may render benefit to their postural impairments and disabilities. In addition, LBP would likely benefit from being considered more than just a musculoskeletal injury; as such, clinicians should consider including approaches that address impairments of postural motor control.
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