The applications and obstacles of metabonomics in traditional chinese medicine.

The applications and obstacles of metabonomics in traditional chinese medicine.
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代谢组学在中医学中的应用及障碍

DOI:
10.1155/2012/945824
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发表时间:
2012
期刊:
Evidence-based complementary and alternative medicine : eCAM
影响因子:
--
通讯作者:
Wang P
Wang P
中科院分区:
其他
文献类型:
--
作者:
Liu P;Liu S;Tian D;Wang P

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近年来,代谢组学技术广泛应用于中药现代研究。目前,中医药研究中最常用的方法主要是核磁共振(NMR)、气相色谱-质谱(GC-MS)和液相色谱-质谱(LC-MS)。代谢组学将有助于中医证候、疗效和毒性的研究。然而,每种分析技术都有其优缺点,在中医药领域的应用还存在一些障碍。因此,本文对代谢组学在中医药研究中的应用进行了探讨,并分析了近年来代谢组学在中医药研究中应用的一些问题。我们相信,随着代谢组学分析技术,特别是多元分析技术的进一步发展,代谢组学将极大地促进中医药研究,有利于中医药现代化。
In the recent years, a wide range of metabonomic technologies are widely used in the modern research of traditional chinese medicine (TCM). At present, the most prevailing methods for TCM research are mainly nuclear magnetic resonance (NMR), gas chromatography-mass spectrometry (GC-MS), and liquid chromatography-mass spectrometry (LC-MS). With these techniques, metabonomics will help to understand syndromes, efficacy and toxicity of TCM. However, every analytical technique has its advantages and drawbacks, and there exist some obstacles of its applications on TCM. So, we discuss metabonomics in TCM and analyze some problems of its applications to study TCM in recent years. We believe that with the further development of metabonomic analytical technology, especially multianalysed techniques, metabonomics will greatly promote TCM research and be beneficial to the modernization of TCM.
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