Diet, Gut Microbiota and COVID-19.

Diet, Gut Microbiota and COVID-19.
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DOI:
10.1007/s12088-020-00908-0
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发表时间:
2020-12
影响因子:
3
通讯作者:
Kalia VC
Kalia VC
中科院分区:
生物学4区
文献类型:
--
作者:
Rishi P;Thakur K;Vij S;Rishi L;Singh A;Kaur IP;Patel SKS;Lee JK;Kalia VC

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在世界范围内,数百万人受到流行的 SARS-CoV-2 的影响。因此,强大的免疫系统仍然是必不可少的,因为免疫功能低下的宿主状态已被证明是致命的。在缺乏任何特定抗病毒药物/疫苗的情况下,已采用 COVID-19 相关药物的重新利用以及各种其他非药物措施以及封锁来对抗这种感染。在这种情况下,大多数印度人食用的富含纤维的植物饮食似乎是有利的,因为它可以用有益微生物补充宿主肠道微生物群,从而形成共生关系,为宿主带来各种健康益处,包括增强免疫力。此外,实施封锁已被证明是一种良好的非药物措施,似乎导致人们食用自制的健康饮食,从而丰富了肠道中的有益微生物群,与西方国家观察到的情况相比,这可能会导致印度 COVID-19 患者的预后更好。
Worldwide, millions of individuals have been affected by the prevailing SARS-CoV-2. Therefore, a robust immune system remains indispensable, as an immunocompromised host status has proven to be fatal. In the absence of any specific antiviral drug/vaccine, COVID-19 related drug repurposing along with various other non-pharmacological measures coupled with lockdown have been employed to combat this infection. In this context, a plant based rich fiber diet, which happens to be consumed by a majority of the Indian population, appears to be advantageous, as it replenishes the host gut microbiota with beneficial microbes thereby leading to a symbiotic association conferring various health benefits to the host including enhanced immunity. Further, implementation of the lockdown which has proven to be a good non-pharmacological measure, seems to have resulted in consumption of home cooked healthy diet, thereby enriching the beneficial microflora in the gut, which might have resulted in better prognosis of COVID-19 patients in India in comparison to that observed in the western countries.
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