A clonal complete remission in a patient with acute nonlymphocytic leukemia originating in a multipotent stem cell.
A clonal complete remission in a patient with acute nonlymphocytic leukemia originating in a multipotent stem cell.
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源自多能干细胞的急性非淋巴细胞白血病患者的克隆完全缓解。
DOI:
10.1056/nejm198406073102307
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发表时间:
1984
期刊:
影响因子:
--
通讯作者:
Fialkow,PJ
中科院分区:
文献类型:
--
作者:
Jacobson,RJ;Temple,MJ;Singer,JW;Raskind,W;Powell,J;Fialkow,PJ
REMISSION after cytotoxic therapy in acute nonlymphocytic leukemia is thought to result from selective destruction of leukemic cells and repopulation of the marrow by normal stem cells. This postulate is supported by the restoration of a normal karyotype in marrow cells and cultured myeloid colonies after chemotherapy.123In addition, in five patients with acute nonlymphocytic leukemia who were heterozygous for glucose-6-phosphate dehydrogenase, only a single enzyme type was found in the leukemic blast cells on initial presentation, but when the patients entered clinical remission, a normal double-enzyme phenotype was observed in mature granulocytes and their precursors.456These findings indicated that . . .
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DOI:
10.1056/nejm197907053010101
发表时间:
1979
期刊:
The New England journal of medicine
影响因子:
--
作者:
P. Fialkow;J. Singer;J. Adamson;R. Berkow;J. Friedman;R. Jacobson;J. Moohr
通讯作者:
J. Moohr
DOI:
10.1172/jci110193
发表时间:
1981
期刊:
The Journal of clinical investigation
影响因子:
--
作者:
Singer,JW;Adamson,JW;Arlin,ZA;Kempin,SJ;Clarkson,BD;Fialkow,PJ
通讯作者:
Fialkow,PJ
DOI:
10.1016/s0308-2261(78)80011-3
发表时间:
1978
期刊:
Clinics in haematology
影响因子:
--
作者:
J. Rowley
通讯作者:
J. Rowley
影响因子:
6.4
作者:
M. Moore;D. Metcalf
通讯作者:
D. Metcalf
影响因子:
20.3
作者:
A. Ferraris;L. Canepa;C. Mareni;G. Baule;T. Meloni;E. Salvidio;G. Forteleoni;G. Gaetani
通讯作者:
G. Gaetani