Time-series analysis for rapid event-related skin conductance responses.

Time-series analysis for rapid event-related skin conductance responses.
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DOI:
10.1016/j.jneumeth.2009.08.005
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发表时间:
2009-11-15
影响因子:
3
通讯作者:
Dolan RJ
Dolan RJ
中科院分区:
医学4区
文献类型:
--
作者:
Bach DR;Flandin G;Friston KJ;Dolan RJ

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事件相关皮肤电导反应(SCR)传统上是通过将单个峰值的幅度与刺激前基线进行比较来分析的。认知神经科学中的许多实验操作都规定了试验间隔短的范例,从而排除了SCR测量的准确基线估计。在这里,我们提出了一种新的和一般的SCR分析方法,源于神经成像中使用的使用线性卷积模型估计反应的方法。实际上,该方法避免了峰值评分,并利用了完整的SCR。我们通过三个实验证明,该方法在分析对巨大白噪声和情绪图片的反应时具有表面有效性,可以推广到响应函数形状未知的范例,并可以解释参数逐次试验效应。我们认为,与现有方法相比,我们的方法在分析SCR方面提供了更大的灵活性。
Event-related skin conductance responses (SCRs) are traditionally analysed by comparing the amplitude of individual peaks against a pre-stimulus baseline. Many experimental manipulations in cognitive neuroscience dictate paradigms with short inter trial intervals, precluding accurate baseline estimation for SCR measurements. Here, we present a novel and general approach to SCR analysis, derived from methods used in neuroimaging that estimate responses using a linear convolution model. In effect, the method obviates peak-scoring and makes use of the full SCR. We demonstrate, across three experiments, that the method has face validity in analysing reactions to a loud white noise and emotional pictures, can be generalised to paradigms where the shape of the response function is unknown and can account for parametric trial-by-trial effects. We suggest our approach provides greater flexibility in analysing SCRs than existing methods.
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发表时间: 2001-04-12
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