Microfluidic behavior of ternary mixed solutions of water/acetonitrile/ethyl acetate through experiments and computer simulations
Microfluidic behavior of ternary mixed solutions of water/acetonitrile/ethyl acetate through experiments and computer simulations
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通过实验和计算机模拟水/乙腈/乙酸乙酯三元混合溶液的微流体行为
DOI：
10.1007/s44211-022-00083-w
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发表时间：
2022
影响因子：
1.6
通讯作者：
Tsukagoshi Kazuhiko
中科院分区：
文献类型：
--
作者：
Yonekura Keigo;Nishimura Kazushi;Tsuchiya Katsumi;Yamashita Kenichi;Murata Masaharu;Tsukagoshi Kazuhiko
当水/乙腈/乙酸乙酯三元混合溶液在层流条件下进入微空间时，溶剂分子表现出特定的微流态流动，如微流态反流和管状径向分布流，这些微流态流动已被应用于新的分析方法中。本文使用混合角为0°、90°、180°和270°的各种y型微通道来研究反向流动。实验观察了反向流动，并通过计算机模拟成功地表达了触发现象。据报道，毛细管中的管径向分布流动，即环状流动，根据三元混合溶液的溶剂组成引起内外相的交换。富有机溶剂的内相和富水的外相以及富水的内相和富有机溶剂的外相的管状径向分布流动可以通过计算机模拟很好地重现。这突出了计算机模拟这种流动场景的有效性，并将允许优化操作条件和微流体分析装置的设计。图形抽象
When ternary mixed solutions of water/acetonitrile/ethyl acetate are delivered into a microspace under laminar flow conditions, the solvent molecules show specific microfluidic flows, such as microfluidic inverted flow and tube radial distribution flow, which have been applied to novel analytical methods. In this paper, inverted flow was examined using various Y-type microchannels that had mixing angles of 0°, 90°, 180°, and 270°. Inverted flow was experimentally observed and the trigger phenomenon was also successfully expressed through computer simulations. Tube radial distribution flow, that is, annular flow, in a capillary tube is reported to cause exchange of the inner and outer phases based on the solvent composition of the ternary mixed solution. Tube radial distribution flow for an organic solvent-rich inner and a water-rich outer phases, as well as for a water-rich inner and an organic solvent-rich outer phases, could be well recreated by computer simulations for a ternary mixed solution. This highlights the effectiveness of computer simulations for such flow scenarios and will allow optimization of the operating conditions and design of microfluidic analytical devices.Graphical abstract
DOI：
10.1016/j.chroma.2004.03.081
发表时间：
2004-07
期刊：
Journal of chromatography. A
影响因子：
--
作者：
Rie Nakashima;S. Kitagawa;Tatsunari Yoshida;T. Tsuda
通讯作者：
Rie Nakashima;S. Kitagawa;Tatsunari Yoshida;T. Tsuda
不同内径双管微流萃取系统的管径向分布现象
DOI：
10.15261/serdj.22.87
发表时间：
2015
期刊：
影响因子：
--
作者：
Katsuya Unesaki;M. Hashimoto;K. Tsukagoshi
通讯作者：
K. Tsukagoshi
将市售高效液相色谱系统与开管毛细管作为分离柱相结合而开发的管径向分布色谱系统。
影响因子：
6.1
作者：
Kento Yamada;Hyo Kan;K. Tsukagoshi
通讯作者：
K. Tsukagoshi