Three-dimensional continuous particle focusing in a microfluidic channel via standing surface acoustic waves (SSAW).
Three-dimensional continuous particle focusing in a microfluidic channel via standing surface acoustic waves (SSAW).
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DOI：
10.1039/c1lc20042a
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发表时间：
2011-07-21
期刊：
影响因子：
6.1
通讯作者：
Huang TJ
中科院分区：
文献类型：
--
作者：
Shi J;Yazdi S;Lin SC;Ding X;Chiang IK;Sharp K;Huang TJ
在单层聚二甲基硅氧烷（PDMS）微流体通道中，利用声表面波（SSAW）实现了三维（3D）连续微粒聚焦。SSAW是由两个平行的叉指换能器（IDT）在压电基板上产生的两个相同的表面声波（SAW）的干涉产生的，其中微通道精确地结合在它们之间。为了理解基于SAW的3D聚焦的工作原理并研究焦点的位置，我们计算了由SAW产生并从微通道的相对侧辐射到流体介质中的纵波，以及由于纵波的干涉和反射而产生的压力和速度场。模拟结果预测了一个聚焦点的存在，这是在很好的协议与我们的实验观察。与其他三维聚焦技术相比，该方法具有无创、鲁棒、节能、易于实现等优点，适用于几乎所有类型的微粒。
Three-dimensional (3D) continuous microparticle focusing has been achieved in a single-layer polydimethylsiloxane (PDMS) microfluidic channel using a standing surface acoustic wave (SSAW). The SSAW was generated by the interference of two identical surface acoustic waves (SAWs) created by two parallel interdigital transducers (IDTs) on a piezoelectric substrate with a microchannel precisely bonded between them. To understand the working principle of the SSAW-based 3D focusing and investigate the position of the focal point, we computed longitudinal waves, generated by the SAWs and radiated into the fluid media from opposite sides of the microchannel, and the resultant pressure and velocity fields due to the interference and reflection of the longitudinal waves. Simulation results predict the existence of a focusing point which is in good agreement with our experimental observations. Compared with other 3D focusing techniques, this method is non-invasive, robust, energy-efficient, easy to implement, and applicable to nearly all types of microparticles.
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影响因子：
6.1
作者：
Ahmed, Daniel;Mao, Xiaole;Huang, Tony Jun
通讯作者：
Huang, Tony Jun
影响因子：
2.8
作者：
Ahmed, Daniel;Mao, Xiaole;Huang, Tony Jun
通讯作者：
Huang, Tony Jun
影响因子：
7.4
作者：
Jacobson, SC;Ramsey, JM
通讯作者：
Ramsey, JM
影响因子：
6.1
作者：
Franke, T.;Braunmueller, S.;Weitz, D. A.
通讯作者：
Weitz, D. A.
DOI：
10.1007/978-0-387-68424-6_9
发表时间：
2007-01-01
期刊：
MICROFLUIDIC TECHNOLOGIES FOR MINIATURIZED ANALYSIS SYSTEMS
影响因子：
--
作者：
Hill, Martyn;Harris, Nicholas R.
通讯作者：
Harris, Nicholas R.