Genome3D: exploiting structure to help users understand their sequences.
Genome3D: exploiting structure to help users understand their sequences.
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DOI：
10.1093/nar/gku973
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发表时间：
2015-01
影响因子：
14.9
通讯作者：
Orengo C
中科院分区：
文献类型：
--
作者：
Lewis TE;Sillitoe I;Andreeva A;Blundell TL;Buchan DW;Chothia C;Cozzetto D;Dana JM;Filippis I;Gough J;Jones DT;Kelley LA;Kleywegt GJ;Minneci F;Mistry J;Murzin AG;Ochoa-Montaño B;Oates ME;Punta M;Rackham OJ;Stahlhacke J;Sternberg MJ;Velankar S;Orengo C
Genome 3D（http：www.genome3d.eu）是一个合作资源，提供关键序列的预测结构域注释和结构模型。自从在之前的NAR论文中引入Genome 3D以来，我们已经大大扩展和改进了资源。我们对Pfam家族的代表进行了注释，以提高对不同序列的覆盖率，并在网站上添加了快速序列搜索功能，使用户能够找到与自己相似的Genome 3D注释序列。我们改进和扩展了Genome 3D数据，将源数据集从3个模式生物扩大到10个，并添加了Genome 3D的新资源VIVACE。我们分析并更新了Genome 3D的SCOP/CATH映射。最后，我们改进了叠加工具，现在为用户提供了一个更强大的界面，用于调查结构模型之间的相似性和差异。
Genome3D (http://www.genome3d.eu) is a collaborative resource that provides predicted domain annotations and structural models for key sequences. Since introducing Genome3D in a previous NAR paper, we have substantially extended and improved the resource. We have annotated representatives from Pfam families to improve coverage of diverse sequences and added a fast sequence search to the website to allow users to find Genome3D-annotated sequences similar to their own. We have improved and extended the Genome3D data, enlarging the source data set from three model organisms to 10, and adding VIVACE, a resource new to Genome3D. We have analysed and updated Genome3D's SCOP/CATH mapping. Finally, we have improved the superposition tools, which now give users a more powerful interface for investigating similarities and differences between structural models.
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影响因子：
14.9
作者：
Sillitoe I;Cuff AL;Dessailly BH;Dawson NL;Furnham N;Lee D;Lees JG;Lewis TE;Studer RA;Rentzsch R;Yeats C;Thornton JM;Orengo CA
通讯作者：
Orengo CA
影响因子：
14.9
作者：
Lees JG;Lee D;Studer RA;Dawson NL;Sillitoe I;Das S;Yeats C;Dessailly BH;Rentzsch R;Orengo CA
通讯作者：
Orengo CA
影响因子：
14.9
作者：
Gough, J;Chothia, C
通讯作者：
Chothia, C
影响因子：
5.6
作者：
TAYLOR, WR;ORENGO, CA
通讯作者：
ORENGO, CA
影响因子：
14.8
作者：
Kelley, Lawrence A.;Sternberg, Michael J. E.
通讯作者：
Sternberg, Michael J. E.