MARGO (Massively Automated Real-time GUI for Object-tracking), a platform for high-throughput ethology
MARGO (Massively Automated Real-time GUI for Object-tracking), a platform for high-throughput ethology
复制标题
MARGO(用于对象跟踪的大规模自动化实时 GUI),高通量行为学平台
DOI:
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发表时间:
2019
期刊:
影响因子:
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通讯作者:
Benjamin L. de Bivort
中科院分区:
文献类型:
--
作者:
Zach Werkhoven;Christian Rohrsen;Chuan Qin;B. Brembs;Benjamin L. de Bivort
Fast object tracking in real time allows convenient tracking of very large numbers of animals and closed-loop experiments that control stimuli for multiple animals in parallel. We developed MARGO, a real-time animal tracking suite for custom behavioral experiments. We demonstrated that MARGO can rapidly and accurately track large numbers of animals in parallel over very long timescales. We incorporated control of peripheral hardware, and implemented a flexible software architecture for defining new experimental routines. These features enable closed-loop delivery of stimuli to many individuals simultaneously. We highlight MARGO’s ability to coordinate tracking and hardware control with two custom behavioral assays (measuring phototaxis and optomotor response) and one optogenetic operant conditioning assay. There are currently several open source animal trackers. MARGO’s strengths are 1) robustness, 2) high throughput, 3) flexible control of hardware and 4) real-time closed-loop control of sensory and optogenetic stimuli, all of which are optimized for large-scale experimentation.
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影响因子:
25
作者:
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通讯作者:
Bethge, Matthias
影响因子:
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通讯作者:
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影响因子:
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