Comparative analysis of breast cancer risk factors among Hispanic and non-Hispanic white women.
Comparative analysis of breast cancer risk factors among Hispanic and non-Hispanic white women.
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DOI：
10.1002/cncr.25154
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发表时间：
2010-07-01
期刊：
影响因子：
6.2
通讯作者：
Byers, Tim
中科院分区：
文献类型：
--
作者：
Hines, Lisa M.;Risendal, Betsy;Slattery, Martha L.;Baumgartner, Kathy B.;Giuliano, Anna R.;Sweeney, Carol;Rollison, Dana E.;Byers, Tim
在美国，西班牙裔和非西班牙裔白色（NHW）人群有不同的乳腺癌发病率，但有有限的研究如何种族差异的患病率确定的危险因素及其与乳腺癌的关联有助于观察到的差异。在以人群为基础的病例对照4角乳腺癌研究中，确定了西班牙裔和NHW女性乳腺癌的比值比和人群归因风险估计值。当比较NHW和西班牙裔妇女时，我们观察到某些危险因素的患病率存在差异，以及它们与乳腺癌相关性的大小和方向。西班牙裔女性更有可能具有与乳腺癌风险较低相关的特征，例如第一次生育的年龄较早，有更多的孩子，身高较低，激素使用较少，饮酒较少。在绝经前妇女中，观察到风险的种族差异与较高的身高和阳性家族史有关，这与西班牙裔妇女中的乳腺癌无关。在绝经后妇女中，与某些危险因素的关联在西班牙裔妇女中要么较弱，要么未观察到，如最近使用雌激素加孕酮激素治疗和初潮年龄较低。在NHW妇女中，估计有62-75%的乳腺癌病例归因于评估的风险因素，而西班牙裔妇女的比例为7-36%。在NHW人群中建立的乳腺癌风险因素对西班牙裔妇女乳腺癌风险的影响较小。这些发现反映了进一步评估不同种族和种族人群中乳腺癌风险因素的必要性。
Hispanic and non-Hispanic white (NHW) populations within the United States have different breast cancer incidence rates, yet there is limited research on how ethnic differences in the prevalence of established risk factors and their associations with breast cancer contribute to the observed differences. Odds ratios and population attributable risk estimates for breast cancer were determined for Hispanic and NHW women in the population-based, case-control 4-Corners Breast Cancer Study. When comparing NHW and Hispanic women, we observed differences in the prevalence of certain risk factors, as well as the magnitude and direction of their associations with breast cancer. Hispanic women were more likely to have characteristics associated with lower breast cancer risk, such as earlier age at first birth, having more children, shorter height, less hormone use, and less alcohol consumption. Among premenopausal women, ethnic differences in risk were observed with taller height and positive family history, which were not associated with breast cancer among Hispanic women. Among postmenopausal women, associations for certain risk factors were either weaker or not observed in Hispanics, such as recent estrogen plus progestin hormone therapy use and younger age at menarche. Among NHW women, an estimated 62-75% of breast cancer cases were attributed to the evaluated risk factors, as compared with 7-36% in Hispanic women. Breast cancer risk factors established in NHW populations had less influence on breast cancer risk in Hispanic women. These findings reflect the need to further evaluate breast cancer risk factors among different ethnic and racial populations.
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影响因子：
2.3
作者：
Risendal, Betsy;Hines, Lisa M.;Sweeney, Carol;Slattery, Martha L.;Giuliano, Anna R.;Baumgartner, Kathy B.;Curtin, Karen;Byers, Tim E.
通讯作者：
Byers, Tim E.
DOI：
10.1093/jnci/87.22.1681
发表时间：
1995-11-15
期刊：
JOURNAL OF THE NATIONAL CANCER INSTITUTE
影响因子：
--
作者：
MADIGAN, MP;ZIEGLER, RG;HOOVER, RN
通讯作者：
HOOVER, RN
影响因子：
3.8
作者：
Chu, KC;Anderson, WF
通讯作者：
Anderson, WF
影响因子：
5
作者：
Gilliland, FD;Hunt, WC;Samet, JM
通讯作者：
Samet, JM
影响因子：
--
作者：
Li, CI;Malone, KE;Daling, JR
通讯作者：
Daling, JR