Local infusion balloon angioplasty to obviate restenosis compared with conventional balloon angioplasty in an experimental model of atherosclerosis.

Local infusion balloon angioplasty to obviate restenosis compared with conventional balloon angioplasty in an experimental model of atherosclerosis.
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在动脉粥样硬化实验模型中,与传统球囊血管成形术相比,局部输注球囊血管成形术可避免再狭窄。

DOI:
10.1016/s0002-8703(07)80009-3
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发表时间:
1993
影响因子:
4.8
通讯作者:
Kernoff,R
Kernoff,R
中科院分区:
医学2区
文献类型:
--
作者:
Stadius,ML;Collins,C;Kernoff,R

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Balloon angioplasty is an accepted treatment for arterial obstruction; however, a substantial percentage of initially successfully treated lesions recur in the first 4 to 6 months. There is increasing interest in local treatment of lesions undergoing angioplasty to prevent restenosis, and an infusion catheter has been developed for this purpose. This study compared infusion balloon angioplasty by means of saline solution with conventional balloon angioplasty in atherosclerotic iliac arteries of 18 cholesterol-fed New Zealand white rabbits. Values for minimum stenosis diameter assessed angiographically immediately after maximum infusion balloon angioplasty (2.1 ± 0.6 mm) and after conventional balloon angioplasty (2.3 ± 0.3 mm,p= NS) were similar. In follow-up studies up to 5 weeks after angioplasty, the angiographic minimum stenosis diameter remained similar in the two treatment groups, but the histologically assessed intimal area was greater after infusion angioplasty (1.54 ± 0.92 mm vs 1.02 ± 0.75 mm in conventionally treated arteries,p= 0.0001). Infusion balloon angioplasty merits further evaluation as a treatment strategy for the simultaneous dilatation of atherosclerotic lesions with delivery of therapeutic agents to minimize restenosis.
DOI: 10.1161/01.atv.12.11.1267
发表时间: 1992
期刊: Arteriosclerosis and thrombosis : a journal of vascular biology
影响因子: --
作者:
M. Stadius;Reed Rowan;J. Fleischhauer;Robert S. Kernoff;M. Billingham;Allen M. Gown
通讯作者: Allen M. Gown
DOI: 10.1016/s0735-1097(88)80046-9
发表时间: 1988-09-01
影响因子: 24
作者:
NOBUYOSHI, M;KIMURA, T;OHISHI, H
通讯作者: OHISHI, H
腔内血管成形术对三种动脉粥样硬化实验模型的急性影响
DOI: --
发表时间: 1982
期刊: Arteriosclerosis
影响因子: --
作者:
D. Faxon;V. J. Weber;C. Haudenschild;S. B. Gottsman;W. A. McGovern;T. Ryan
通讯作者: T. Ryan
实验性动脉粥样硬化经腔血管成形术后的再狭窄。
DOI: --
发表时间: 1984
期刊: Arteriosclerosis
影响因子: --
作者:
D. Faxon;T. Sanborn;V. J. Weber;C. Haudenschild;S. B. Gottsman;W. A. McGovern;T. Ryan
通讯作者: T. Ryan
DOI: --
发表时间: 1989
期刊:
影响因子: --
作者:
H. Wolinsky;S. Thung
通讯作者: S. Thung