Thyroid ultrasound findings in children from three Japanese prefectures: Aomori, Yamanashi and Nagasaki.
Thyroid ultrasound findings in children from three Japanese prefectures: Aomori, Yamanashi and Nagasaki.
复制标题
DOI：
10.1371/journal.pone.0083220
复制
发表时间：
2013
期刊：
影响因子：
3.7
通讯作者：
Investigation Committee for the Proportion of Thyroid Ultrasound Findings
中科院分区：
文献类型：
--
作者：
Hayashida N;Imaizumi M;Shimura H;Okubo N;Asari Y;Nigawara T;Midorikawa S;Kotani K;Nakaji S;Otsuru A;Akamizu T;Kitaoka M;Suzuki S;Taniguchi N;Yamashita S;Takamura N;Investigation Committee for the Proportion of Thyroid Ultrasound Findings
由于福岛第一核电站前所未有的事故可能对身心健康造成影响，福岛县政府决定进行福岛健康管理调查，以协助居民的长期健康管理。这包括对福岛所有儿童进行甲状腺超声检查。为了正确评价甲状腺超声筛查，了解其对儿童甲状腺检查的参考资料是很重要的。为了分析特定甲状腺发现的频率，我们对来自日本三个县的4365名3至18岁的儿童进行了甲状腺超声筛查，采用与福岛相同的程序。总体而言，56.88%的参与者发现了甲状腺囊肿，1.65%的参与者发现了甲状腺结节。最大直径大于5mm的甲状腺囊肿和结节的检出率分别为4.58%和1.01%，年龄调整后的检出率分别为3.82%和0.99%。虽然不同检查区域的囊肿和结节患病率不同，但最大直径大于5mm的囊肿和结节患病率在三个检查区域之间没有显著差异。甲状腺囊肿和结节的患病率，尤其是最大直径大于5mm的囊肿和结节，随着年龄的增长而显著增加，且以女性为主。我们还发现异位胸腺（1.95%）、弥漫性甲状腺肿（1.40%）、多鳃体（0.73%）、淋巴结肿胀（0.21%）和甲状腺发育不全（0.05%）。这是第一次超声描述年龄调整后的甲状腺囊肿和结节患病率，或者是与年龄相关的除囊肿和结节以外的异常患病率，如胸腺异位。我们认为，这可以为福岛健康管理调查和未来的人口研究提供相关信息。
Due to the likelihood of physical and mental health impacts following the unprecedented accident at the Fukushima Dai-ichi Nuclear Power Plant, the Fukushima prefectural government decided to conduct the Fukushima Health Management Survey to assist in the long-term health management of residents. This included thyroid ultrasound examination for all children in Fukushima. For appropriate evaluation of ultrasound screening of the thyroid, it is important to understand its reference data of thyroid findings in children in general. In order to analyze the frequencies of specific thyroid findings, we conducted ultrasound screening of the thyroid by the same procedures as used in Fukushima in 4,365 children, aged 3 to 18 years, from three Japanese prefectures. Overall, thyroid cysts were identified in 56.88% and thyroid nodules in 1.65% of the participants. Thyroid cysts and nodules with a maximum diameter of more than 5 mm were identified in 4.58% and 1.01%, respectively, and age-adjusted prevalences were 3.82% and 0.99%, respectively. Although the prevalence of cysts and nodules varied among the examination areas, no significant differences were observed among the three examination areas in the prevalence of cysts and nodules with a maximum diameter of more than 5 mm. Also, the prevalence of thyroid cysts and nodules, especially those with a maximum diameter of more than 5 mm, significantly increased with age, and showed a female predominance. We also identified ectopic thymus (1.95%), diffuse goiter (1.40%), ultimobranchial body (0.73%), lymph node swelling (0.21%) and thyroid agenesis (0.05%). This is the first ultrasound description of the age-adjusted prevalence of thyroid cysts and nodules, or of the prevalence of abnormalities other than cysts and nodules, such as ectopic thymus, in relation to age, in the general Japanese child population. We contend that this can provide relevant information for the Fukushima Health Management Survey and future population studies.
登录
查看更多内容
影响因子：
4.7
作者：
Yasumura S;Hosoya M;Yamashita S;Kamiya K;Abe M;Akashi M;Kodama K;Ozasa K;Fukushima Health Management Survey Group
通讯作者：
Fukushima Health Management Survey Group
影响因子：
3.7
作者：
Taira Y;Hayashida N;Yamaguchi H;Yamashita S;Endo Y;Takamura N
通讯作者：
Takamura N
影响因子：
6.6
作者：
Kang, HW;No, JH;Kim, KW
通讯作者：
Kim, KW
影响因子：
39.2
作者：
Tan, GH;Gharib, H
通讯作者：
Gharib, H
影响因子：
2
作者：
Ishigaki, K;Namba, H;Yamashita, S
通讯作者：
Yamashita, S