The pleasures of play: pharmacological insights into social reward mechanisms.

The pleasures of play: pharmacological insights into social reward mechanisms.
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DOI:
10.1016/j.tips.2010.06.008
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发表时间:
2010-10
影响因子:
13.8
通讯作者:
Vanderschuren LJ
Vanderschuren LJ
中科院分区:
医学1区
文献类型:
--
作者:
Trezza V;Baarendse PJ;Vanderschuren LJ

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像人类的孩子一样,大多数年轻的哺乳动物花了大量的时间和精力在一起玩耍,社交游戏很有趣。虽然社交游戏是非常愉快的,但它不仅仅是一种轻浮的活动:它对行为灵活性的发展,社交和认知能力的获得以及群体凝聚力的维持至关重要。社交游戏是一种天然的强化剂,与自然和药物奖励的动机、愉悦和认知方面密切相关的神经递质系统,例如阿片类药物、内源性大麻素、多巴胺和去甲肾上腺素,在社交游戏的表现中发挥着重要的调节作用。在这篇综述中,我们将讨论社会游戏是有益的概念,并讨论这种行为的神经药理学的最新进展。这提供了一个框架,以了解大脑如何处理社会情绪,使年轻人享受社会游戏。
Like human children, most young mammals devote a significant amount of time and energy playing together, and social play is fun. Although social play is very pleasurable, it is more than just a frivolous activity: it is crucial for the development of behavioral flexibility, the acquisition of social and cognitive competence and the maintenance of group cohesion. Social play is a natural reinforcer, and the neurotransmitter systems intimately implicated in the motivational, pleasurable and cognitive aspects of natural and drug rewards, such as opioids, endocannabinoids, dopamine and noradrenaline, play an important modulatory role in the performance of social play as well. In this review, we will address the notion that social play is rewarding, and discuss recent developments in the neuropharmacology of this behavior. This provides a framework to understand how the brain processes social emotions, to make young individuals enjoy social play.
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