Prevalence and associated factors of erectile dysfunction, psychological disorders, and sexual performance in primary vs. secondary infertility men.

Prevalence and associated factors of erectile dysfunction, psychological disorders, and sexual performance in primary vs. secondary infertility men.
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原发性与继发性不育男性勃起功能障碍、心理障碍和性能力的患病率及相关因素

DOI:
10.1186/s12958-021-00720-5
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发表时间:
2021-03-09
期刊:
Reproductive biology and endocrinology : RB&E
影响因子:
--
通讯作者:
Wang B
Wang B
中科院分区:
其他
文献类型:
--
作者:
Ma J;Zhang Y;Bao B;Chen W;Li H;Wang B

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中国继发不孕症患者资料有限,但许多不育夫妇可能会出现勃起功能障碍(ED),性生活质量和心理状态发生显着变化。目的探讨原发不孕症或继发性不孕症与勃起功能障碍、心理障碍、性行为的关系。方法在北京中医药大学东直门医院进行横断面调查(2019年6月-2020年1月)。参与者完成了一份问卷,包括一般信息、性生活、简化国际勃起功能指数(IIEF-5)、患者健康问卷-9(PHQ-9)和7项广泛性焦虑障碍量表(GAD-7)。结果ED在继发性不孕症中的发生率高于原发不孕症(46.5 %vs.26.7 %,P< 0.001)。与原发不孕症患者相比,继发性不孕症患者IIEF-5评分较低(P< 0.001),TOIF发生率较高(P= 0.001),勃起功能障碍时对配偶排卵的知晓率较高(P= 0.001),GAD-7评分较低(P= 0.016),性欲较低(P= 0.005),每月性交次数较少(P= 0.001),性满意度评分较低(P= 0.027)。在多因素分析中,原发不孕症是焦虑的独立危险因素(OR:1.812,95 %CI:1.015~3.236)。原发不孕症与继发性不孕症患者的勃起功能障碍、心理障碍、性行为等相关因素有一定的重叠性,但也有一定差异。结论继发性不育症男性勃起功能障碍的患病率高于原发不育症男性,性生活质量下降。原发不孕症是焦虑的独立危险因素。
BackgroundMany infertile couples might experience erectile dysfunction (ED) and significant changes in the quality of sexual life and psychological state though information is limited in secondary infertile men in China. To determine whether primary or secondary infertility is associated with ED, psychological disorders, and sexual performance.MethodsThis was a cross-sectional survey conducted at the Dongzhimen Hospital of Beijing University of Chinese Medicine (06/2019-01/2020). The participants completed a questionnaire including general information, sexual life, simplified International Index of Erectile Function (IIEF-5), Patient Health Questionnaire-9 (PHQ-9), and 7-item Generalized Anxiety Disorder Scale (GAD-7). Multivariable logistic regression was used to identify the factors associated with ED, depression, and anxiety.ResultsED was more frequent in secondary vs. primary infertility (46.5 % vs. 26.7 %,P< 0.001). Compared with men with primary infertility, those with secondary infertility showed lower IIEF-5 scores (P< 0.001), higher occurrence of TOIF (P= 0.001), had a higher awareness of partner’s ovulation when having ED (P= 0.001), lower GAD-7 scores (P= 0.016), lower libido (P= 0.005), fewer intercourses per month (P= 0.001) and a lower sexual satisfaction score (P= 0.027). In the multivariate analysis, primary infertility was found to be an independent risk factor of anxiety (OR: 1.812, 95 %CI: 1.015–3.236). Some overlap is observed in factors associated with ED, psychological disorders, and sexual performance between primary and secondary infertility, but some factors are distinct.ConclusionsThe prevalence of ED in secondary infertility men was higher than that of primary infertility men, and the quality of sexual life was decreased. Primary infertility is an independent risk factor of anxiety.
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