The mediating effect of parental neglect on adolescent and young adult anti-sociality: a longitudinal study of twins and their parents.

The mediating effect of parental neglect on adolescent and young adult anti-sociality: a longitudinal study of twins and their parents.
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DOI:
10.1007/s10519-010-9336-2
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发表时间:
2010-07
期刊:
影响因子:
2.6
通讯作者:
Silberg, Judy L.
Silberg, Judy L.
中科院分区:
医学3区
文献类型:
--
作者:
Eaves, Lindon J.;Prom, Elizabeth C.;Silberg, Judy L.

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由于典型的家庭研究中遗传因素和社会因素是相关的,因此父母对待与后代行为之间相关性的原因并不明确。由于需要描述基因和环境对青少年和成人行为结果的影响,问题变得更加复杂。针对青少年和成年双胞胎及其父母之间的相似性开发了一个模型,可以解决其中一些影响。从 1,412 个青少年和青年双胞胎家庭中获得了有关童年逆境、父母反社会行为以及纵向成人和青少年反社会行为的数据。建立了一个结构模型,考虑到从父母到孩子的遗传和社会信息传递的影响。父母的环境影响可以通过测量家庭环境的特征来调节。参数是通过对角加权最小二乘法估计的,该最小二乘法应用于亲属之间以及年龄内和年龄之间的变量之间的 33 个不同的多向相关性。测试了子假设。结果证实基因和环境的影响都非常显着。遗传效应在青少年中很大,并且主要与年龄和性别有关。大约 30% 的共同环境造成的差异是由于童年逆境的影响。其余的共同环境影响尚无法解释。逆境很大程度上受到母亲反社会行为的影响。父亲的 ASP 与逆境之间的相关性可以通过反社会的父亲选择(或创造)反社会的母亲来解释。父母 ASP 对环境的所有重大影响都是通过逆境的衡量来调节的。尽管 ASP 的传播既是遗传性的,也是社会性的,但被动基因型与环境的相关性非常小。 ASP 的选型交配对兄弟姐妹之间的遗传相关性几乎没有检测到影响。对双胞胎及其父母的纵向研究使证明童年逆境对儿童行为障碍的直接因果影响超过任何间接的遗传相关性成为可能。
The causes of correlation between parental treatment and offspring behavior are ambiguous since genetic and social factors are correlated in typical family studies. The problem is complicated by the need to characterize the effects of genes and environment on both juvenile and adult behavioral outcomes. A model is developed for the resemblance between juvenile and adult twins and their parents that allows some of these effects to be resolved. Data on childhood adversity, parental antisocial behavior, and longitudinal adult and juvenile anti-social behavior were obtained from 1,412 families of adolescent and young adult twins. A structural model is fitted that allows for the effects of genetic and social transmission of information from parents to children. Environmental effects of parents may be mediated through measured features of the home environment. Parameters were estimated by diagonal weighted least squares applied to the 33 distinct polychoric correlations between relatives and between variables within and between ages. Sub-hypotheses were tested. Results confirmed that effects of genes and environment were both highly significant. Genetic effects were large in juveniles and largely age and sex-specific. Approximately 30% of the variation due to the shared environment was due to the effect of childhood adversity. The remaining shared environmental effects are unexplained. Adversity is affected significantly by maternal anti-social behavior. The correlation between paternal ASP and adversity may be explained by antisocial fathers selecting (or creating) antisocial mothers. All significant environmental effects of parental ASP are mediated through the measure of adversity. Though transmission of ASP is both genetic and social, passive genotype–environment correlation is very small. Assortative mating for ASP has barely detectable consequence for the genetic correlation between siblings. The longitudinal study of twins and their parents makes it possible to demonstrate there is a direct causal effect of childhood adversity on child conduct disorder over and above any indirect genetic correlation.
DOI: 10.1111/1469-7610.00196
发表时间: 2003-11-01
期刊: JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY AND ALLIED DISCIPLINES
影响因子: --
作者:
D'Onofrio, BM;Turkheimer, EN;Emery, RE
通讯作者: Emery, RE
DOI: 10.1007/s10519-005-7284-z
发表时间: 2005-11-01
期刊: BEHAVIOR GENETICS
影响因子: 2.6
作者:
Eaves, L;Erkanli, A;Foley, D
通讯作者: Foley, D
DOI: 10.1038/hdy.1981.30
发表时间: 1981-01-01
期刊: HEREDITY
影响因子: 3.8
作者:
HALEY, CS;JINKS, JL;LAST, K
通讯作者: LAST, K
DOI: 10.1017/s0033291799002408
发表时间: 2000-07-01
影响因子: 6.9
作者:
Meyer, JM;Rutter, M;Eaves, LJ
通讯作者: Eaves, LJ
DOI: 10.1375/twin.8.4.283
发表时间: 2005-08-01
影响因子: 0.9
作者:
Eaves, LJ;Silberg, JL;Maes, HH
通讯作者: Maes, HH