Using informatics to advance translational science: Environmental scan of adaptive capacity and preparedness of Clinical and Translational Science Award Program hubs.

Using informatics to advance translational science: Environmental scan of adaptive capacity and preparedness of Clinical and Translational Science Award Program hubs.
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DOI:
10.1017/cts.2022.402
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发表时间:
2022
影响因子:
2.6
通讯作者:
Holmes, Kristi
Holmes, Kristi
中科院分区:
其他
文献类型:
--
作者:
Ragon, Bart;Volkov, Boris B.;Pulley, Chris;Holmes, Kristi

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在美国和世界其他国家竞相抗击COVID-19大流行之际,国家促进转化科学中心多年来的投资使CTSA中心的信息服务和资源能够在应对危机方面发挥重要作用。CTSA中心与当地和区域合作伙伴合作,收集有关大流行的数据,提供相关患者数据,并制作数据仪表板以支持决策。国家COVID队列协作(N3C)等协调努力帮助汇总和协调了全国的临床数据。即使有了大量的信息投资,一些CTSA中心仍感到在应对快速发展的公共卫生危机方面能力不足。许多枢纽被迫迅速发展以满足当地需求。信息学团队扩大了其所在机构的关键支持,包括临床研究参与平台、社区COVID-19认识和教育活动以及COVID-19数据仪表板。对信息学资源的持续投资将有助于确保工具、资源、做法和政策协调一致,以满足地方和国家的公共卫生需求。
As the USA and the rest of the world raced to fight the COVID-19 pandemic, years of investments from the National Center for Advancing Translational Sciences allowed for informatics services and resources at CTSA hubs to play a significant role in addressing the crisis. CTSA hubs partnered with local and regional partners to collect data on the pandemic, provide access to relevant patient data, and produce data dashboards to support decision-making. Coordinated efforts, like the National COVID Cohort Collaborative (N3C), helped to aggregate and harmonize clinical data nationwide. Even with significant informatics investments, some CTSA hubs felt unprepared in their ability to respond to the fast-moving public health crisis. Many hubs were forced to quickly evolve to meet local needs. Informatics teams expanded critical support at their institutions which included an engagement platform for clinical research, COVID-19 awareness and education activities in the community, and COVID-19 data dashboards. Continued investments in informatics resources will aid in ensuring that tools, resources, practices, and policies are aligned to meet local and national public health needs.
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