Immunocytochemical localization of luteinizing hormone-releasing hormone and proopiomelanocortin neurons within the preoptic area and hypothalamus of the bovine brain.
Immunocytochemical localization of luteinizing hormone-releasing hormone and proopiomelanocortin neurons within the preoptic area and hypothalamus of the bovine brain.
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牛脑视前区和下丘脑内黄体生成素释放激素和阿黑皮素原神经元的免疫细胞化学定位。
DOI：
10.1095/biolreprod39.4.963
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发表时间：
1988
影响因子：
3.6
通讯作者：
T. Kiser
中科院分区：
文献类型：
--
作者：
L. S. Leshin;L. Rund;J. W. Crim;T. Kiser
研究了青春期前雌性小牛和成熟黄体期母牛脑组织中前阿黑皮素（POMC）和促黄体生成激素释放激素（LHRH）神经元的解剖位置。生物素-抗生物素蛋白-过氧化物酶程序用于单标记和双标记免疫染色。LHRH胞体形成一个松散排列的连续体，从Broca斜角带向后延伸，穿过内侧和外侧视前区，并在下丘脑前区内结束。LHRH纤维明显指向正中隆起，（1）在室周区后腹侧穿过弓状核，（2）在弓状核的腹内侧外侧和视上核的内侧。POMC胞体位于弓状核内及周围，部分穿入正中隆起。纤维从这些POMC胞体腹侧通过终止于正中隆起和区域腹侧的乳头核。POMC纤维也从弓状核向背侧和外侧投射到下丘脑其他区域，并沿第三脑室壁向前沿着投射到视前区、终纹床核和终纹。不到6%的POMC或LHRH过程中密切解剖对位LHRH胞体和树突。LHRH和POMC纤维在正中隆起的腹外侧广泛混杂。
The anatomical locations of proopiomelanocortin (POMC) and luteinizing hormone-releasing hormone (LHRH) neurons were examined in brain tissue from peripubertal female calves and from mature, luteal-phase cows. Biotin-avidin-peroxidase procedures were used for single- and double-labeled immunostaining. LHRH perikarya formed a loosely arranged continuum, extending posteriorly from the diagonal band of Broca, passing through the medial and lateral preoptic areas, and ending within the anterior hypothalamic area. LHRH fibers, apparently directed toward the median eminence, passed (1) posteroventrally in the periventricular area and through the arcuate nucleus, and (2) ventromedially lateral to the arcuate nucleus and medial to the supraoptic nucleus. POMC perikarya were located within and about the arcuate nucleus, some penetrating into the median eminence. Fibers from these POMC perikarya passed ventrally to terminate in the median eminence and to regions ventral to the mammillary nuclei. POMC fibers also projected dorsally and laterally from the arcuate nucleus to other hypothalamic regions as well as anteriorly along the third ventricular wall to the preoptic area, bed nucleus of stria terminalis, and stria terminalis. Less than 6% of the POMC or LHRH processes were in close anatomical apposition to LHRH perikarya and dendrites. Extensive intermingling of LHRH and POMC fibers occurred within zona externa of the median eminence.
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影响因子：
4.1
作者：
J. Witkin;C. Paden;A. Silverman
通讯作者：
J. Witkin;C. Paden;A. Silverman
吗啡对恒河猴下丘脑黄体生成素释放激素脉冲发生器电生理活性的影响。
影响因子：
4.1
作者：
Kesner,JS;Kaufman,JM;Wilson,RC;Kuroda,G;Knobil,E
通讯作者：
Knobil,E
mu-、delta-和 kappa-阿片受体的特异性激活对卵巢切除大鼠黄体生成素和催乳素分泌的影响。
影响因子：
4.1
作者：
Leadem,CA;Yagenova,SV
通讯作者：
Yagenova,SV
未成熟雄性大鼠下丘脑与成年雄性大鼠下丘脑对二丁酰环 AMP 和毛喉素诱导的体外 LHRH 释放的反应性。
影响因子：
4.1
作者：
Hartter,DE;Ramirez,VD
通讯作者：
Ramirez,VD
内侧基底下丘脑中含有β-内啡肽或强啡肽的神经元的子集会积累雌二醇。
影响因子：
4.1
作者：
Morrell,JI;McGinty,JF;Pfaff,DW
通讯作者：
Pfaff,DW