Quantitative comparison and metabolite profiling of saponins in different parts of the root of Panax notoginseng.
Quantitative comparison and metabolite profiling of saponins in different parts of the root of Panax notoginseng.
复制标题
DOI：
10.1021/jf502214x
复制
发表时间：
2014-09-10
影响因子：
6.1
通讯作者：
Jiang ZH
中科院分区：
文献类型：
--
作者：
Wang JR;Yau LF;Gao WN;Liu Y;Yick PW;Liu L;Jiang ZH
三七的根茎和根在《中国药典》中都被正式用作三七，但在实践中对三七的不同部位有不同的用法。为了给药用的差异化利用提供化学依据，对不同来源的根茎和商品样品进行了定量比较和代谢产物谱分析，结果表明，根茎中皂苷的含量总体上较高，其次是主根、枝根和须根。人参皂苷Rb2的含量为0.5 mg/g，可作为区分根茎和其他部位的潜在标记。代谢产物图谱的多变量分析进一步表明，32个三七皂苷可作为三七不同部位的潜在鉴别标志。综上所述，本研究为三七不同部位的不同用途提供了全面的化学证据，对合理利用和开发三七各部位具有重要意义。
Although both rhizome and root of Panax notoginseng are officially utilized as notoginseng in “Chinese Pharmacopoeia”, individual parts of the root were differently used in practice. To provide chemical evidence for the differentiated usage, quantitative comparison and metabolite profiling of different portions derived from the whole root, as well as commercial samples, were carried out, showing an overall higher content of saponins in rhizome, followed by main root, branch root, and fibrous root. Ginsenoside Rb2 was proposed as a potential marker with a content of 0.5 mg/g as a threshold value for differentiating rhizome from other parts. Multivariate analysis of the metabolite profile further suggested 32 saponins as potential markers for the discrimination of different parts of notoginseng. Collectively, the study provided comprehensive chemical evidence for the distinct usage of different parts of notoginseng and, hence, is of great importance for the rational application and exploitation of individual parts of notoginseng.
登录
查看更多内容
一种来自三七根的新原人参二醇型人参皂苷
影响因子：
1.7
作者：
Fu, Hui-Zheng;Zhong, Rui-Jian;Wang, Dong
通讯作者：
Wang, Dong
DOI：
10.3736/jcim20120303
发表时间：
2012-03-01
期刊：
Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine
影响因子：
--
作者：
Han, Jin-bin;Hua, Yong-qiang;Liu, Lu-ming
通讯作者：
Liu, Lu-ming
影响因子：
6.1
作者：
Liao, Peng-Ying;Wang, Dong;Yang, Chong-Ren
通讯作者：
Yang, Chong-Ren
影响因子：
6.1
作者：
Liu, Ji-Hua;Lee, Che-Sum;Jiang, Zhi-Hong
通讯作者：
Jiang, Zhi-Hong
影响因子：
1.7
作者：
Pei, Ying;Du, Qian;Zhang, Ying-Jun
通讯作者：
Zhang, Ying-Jun