Mouse Genome Database (MGD) 2019.

Mouse Genome Database (MGD) 2019.
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DOI:
10.1093/nar/gky1056
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发表时间:
2019-01-08
影响因子:
14.9
通讯作者:
Mouse Genome Database Group
Mouse Genome Database Group
中科院分区:
生物学2区
文献类型:
--
作者:
Bult CJ;Blake JA;Smith CL;Kadin JA;Richardson JE;Mouse Genome Database Group

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小鼠基因组数据库(MGd;http://www.informatics.jax.org))是实验室小鼠的社区模式生物遗传和基因组资源。MGD是与小鼠基因、基因功能、表型和人类疾病小鼠模型相关的生物参考数据集的权威来源。MGD是根据国际小鼠标准化命名委员会制定的指南进行官方基因、等位基因和小鼠品系命名的主要渠道。在这份报告中,我们描述了MGD的重大增强,包括两个新的图形用户界面:(I)用于探索多个小鼠品系基因组的多基因组查看器和(Ii)与基因表达数据库(GXD)合作开发的表型-基因表达矩阵,它允许研究人员比较小鼠基因的基因表达和表型注释。最近的其他改进包括提高了我们的文献整理过程的效率,以及纳入了RIKEN的FANTOM 5倡议的转录起始站点(TSS)注释。
The Mouse Genome Database (MGD; http://www.informatics.jax.org) is the community model organism genetic and genome resource for the laboratory mouse. MGD is the authoritative source for biological reference data sets related to mouse genes, gene functions, phenotypes, and mouse models of human disease. MGD is the primary outlet for official gene, allele and mouse strain nomenclature based on the guidelines set by the International Committee on Standardized Nomenclature for Mice. In this report we describe significant enhancements to MGD, including two new graphical user interfaces: (i) the Multi Genome Viewer for exploring the genomes of multiple mouse strains and (ii) the Phenotype-Gene Expression matrix which was developed in collaboration with the Gene Expression Database (GXD) and allows researchers to compare gene expression and phenotype annotations for mouse genes. Other recent improvements include enhanced efficiency of our literature curation processes and the incorporation of Transcriptional Start Site (TSS) annotations from RIKEN’s FANTOM 5 initiative.
DOI: 10.1101/gr.234096.117
发表时间: 2018-04
期刊: Genome research
影响因子: 7
作者:
Thybert D;Roller M;Navarro FCP;Fiddes I;Streeter I;Feig C;Martin-Galvez D;Kolmogorov M;Janoušek V;Akanni W;Aken B;Aldridge S;Chakrapani V;Chow W;Clarke L;Cummins C;Doran A;Dunn M;Goodstadt L;Howe K;Howell M;Josselin AA;Karn RC;Laukaitis CM;Jingtao L;Martin F;Muffato M;Nachtweide S;Quail MA;Sisu C;Stanke M;Stefflova K;Van Oosterhout C;Veyrunes F;Ward B;Yang F;Yazdanifar G;Zadissa A;Adams DJ;Brazma A;Gerstein M;Paten B;Pham S;Keane TM;Odom DT;Flicek P
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发表时间: 2019-01-08
影响因子: 14.9
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发表时间: 2009-09-01
期刊: GENOME RESEARCH
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发表时间: 2019-01-08
影响因子: 14.9
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DOI: 10.1093/nar/gkw1073
发表时间: 2017-01-04
影响因子: 14.9
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