Effect of chyme viscosity and nutrient feedback mechanism on gastric emptying.

Effect of chyme viscosity and nutrient feedback mechanism on gastric emptying.
复制标题

Chyme粘度和养分反馈机制对胃排空的影响。

DOI:
10.1016/j.ces.2017.05.048
复制
发表时间:
2017-11-02
影响因子:
4.7
通讯作者:
Bakalis S
Bakalis S
中科院分区:
工程技术2区
文献类型:
--
作者:
Moxon TE;Nimmegeers P;Telen D;Fryer PJ;Van Impe J;Bakalis S

文献摘要

参考文献

被引文献

相似文献

胃排空率通过反馈机制与肠道生物可及性相关。胃分泌模型将分泌速率与胃粘度联系起来。型号适用于低粘度和高粘度液体餐的排空。人类消化过程的综合数学模型可以更好地设计功能性食品,这可能在遏制世界各地与食物有关的疾病的流行方面发挥作用。这项工作提出了一个数学模型的营养为基础的反馈机制控制胃排空,这已经确定在体内的许多研究人员。该模型还考虑了胃分泌物和排空时营养餐的粘度。结果表明,模拟的营养反馈机制作为一个开/关系统,与初始排空率依赖于分泌速率(这是一个函数的胃食糜粘度)提供了一个很好的适合的趋势排空率的液体餐的低和高营养含量与不同的粘度。
Gastric emptying rate linked to intestinal bioaccessability by feedback mechanism. Gastric secretion model links the secretion rate to the gastric viscosity. Model fits emptying of low and high viscosity liquid meals. A comprehensive mathematical model of the digestive processes in humans could allow for better design of functional foods which may play a role in stemming the prevalence of food related diseases around the world. This work presents a mathematical model for a nutrient based feedback mechanism controlling gastric emptying, which has been identified in vivo by numerous researchers. The model also takes into account the viscosity of nutrient meals upon gastric secretions and emptying. The results show that modelling the nutrient feedback mechanism as an on/off system, with an initial emptying rate dependent upon the secretion rate (which is a function of the gastric chyme viscosity) provides a good fit to the trends of emptying rate for liquid meals of low and high nutrient content with varying viscosity.
DOI: 10.1016/j.physbeh.2004.07.014
发表时间: 2004-10-30
影响因子: 2.9
作者:
de Wijk, RA;Prinz, JF;Weenen, H
通讯作者: Weenen, H
DOI: 10.1136/gutjnl-2013-305112
发表时间: 2014-01-01
期刊: GUT
影响因子: 24.5
作者:
Depoortere, Inge
通讯作者: Depoortere, Inge
DOI: 10.1016/j.bpg.2014.10.006
发表时间: 2014-12-01
影响因子: 3.2
作者:
Di Mario, Francesco;Goni, Elisabetta
通讯作者: Goni, Elisabetta
DOI: 10.1111/j.1440-1746.2011.06627.x
发表时间: 2011-04-01
影响因子: 4.1
作者:
Kusano, Motoyasu;Zai, Hiroaki;Mori, Masatomo
通讯作者: Mori, Masatomo
DOI: 10.1136/gut.18.2.105
发表时间: 1977-01-01
期刊: GUT
影响因子: 24.5
作者:
GROTZINGER, U;BERGEGARDH, S;OLBE, L
通讯作者: OLBE, L