Biofilms and their engineered counterparts: A new generation of immobilised biocatalysts

Biofilms and their engineered counterparts: A new generation of immobilised biocatalysts
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生物膜及其工程对应物:新一代固定化生物催化剂

DOI:
10.1039/c2cy20085f
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发表时间:
2012
影响因子:
5
通讯作者:
Winn M
Winn M
中科院分区:
化学2区
文献类型:
--
作者:
Winn M

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生物膜的坚固性质使它们在医学上难以处理,然而,这种相同的性质使它们成为保护和固定用于生物转化的酶的有吸引力的方法。尽管由不同微生物物种的聚生体组成的生物膜已经常规地用于水净化几十年,但是很少有报道的将单一物种生物膜用于工业应用的实例。使用定制的单一物种生物膜,以催化选择的生物转化的潜力是有吸引力的,我们反映在使用和生成这样的平台,从生物和工艺工程的角度来看,最近的进展。
The robust nature of biofilms makes them medicinally difficult to treat, however this same property renders them an attractive method for protecting and immobilising enzymes for biotransformation. Although biofilms consisting of a consortium of different microbial species have been routinely used in water purification for many decades, there are few reported examples of single species biofilms being harnessed for industrial applications. The potential of using tailored single species biofilms in order to catalyse a biotransformation of choice is attractive; we reflect upon recent advances in the use and generation of such platforms, from both biological and process engineering viewpoints.
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