Rhinosinusitis: Establishing definitions for clinical research and patient care.
Rhinosinusitis: Establishing definitions for clinical research and patient care.
复制标题
DOI：
10.1016/j.otohns.2004.09.067
复制
发表时间：
2004-12
期刊：
影响因子：
--
通讯作者：
American Rhinologic Society
中科院分区：
文献类型：
--
作者：
Meltzer EO;Hamilos DL;Hadley JA;Lanza DC;Marple BF;Nicklas RA;Bachert C;Baraniuk J;Baroody FM;Benninger MS;Brook I;Chowdhury BA;Druce HM;Durham S;Ferguson B;Gwaltney JM Jr;Kaliner M;Kennedy DW;Lund V;Naclerio R;Pawankar R;Piccirillo JF;Rohane P;Simon R;Slavin RG;Togias A;Wald ER;Zinreich SJ;American Academy of Allergy, Asthma and Immunology;American Academy of Otolaryngic Allergy;American Academy of Otolaryngology-Head and Neck Surgery;American College of Allergy, Asthma and Immunology;American Rhinologic Society
有必要对所有形式的鼻窦炎进行更多的研究。这一领域的进展一直受到缺乏共识定义和有限数量的临床试验发表的阻碍。建立鼻窦炎的共识定义，并概述临床试验中有用的策略。美国过敏、哮喘和免疫学会、美国耳鼻喉科过敏学会、美国耳鼻喉科头颈外科学会、美国过敏、哮喘和免疫学会以及美国鼻科学会等五个国家学会组成了一个来自多个学科的专家小组。在两天的时间里，专家组制定了鼻窦炎的定义，并概述了临床试验设计的策略。委员会成员同意采用“鼻窦炎”这一术语，并就急性假定细菌性鼻窦炎、慢性鼻窦炎不伴息肉病、慢性鼻窦炎伴息肉病和经典变应性真菌性鼻窦炎的定义和临床研究策略达成共识。症状和客观标准，监测研究进展的措施，并使用症状评分工具，生活质量的工具，放射学研究，和内窥镜评估概述了每种条件。本次会议的建议应提高临床诊断的准确性，并作为鼻窦炎临床试验设计的起点。
There is a need for more research on all forms of rhinosinusitis. Progress in this area has been hampered by a lack of consensus definitions and the limited number of published clinical trials. To develop consensus definitions for rhinosinusitis and outline strategies useful in clinical trials. Five national societies, The American Academy of Allergy, Asthma and Immunology; The American Academy of Otolaryngic Allergy; The American Academy of Otolaryngology Head and Neck Surgery; The American College of Allergy, Asthma and Immunology; and the American Rhinologic Society formed an expert panel from multiple disciplines. Over two days, the panel developed definitions for rhinosinusitis and outlined strategies for design of clinical trials. Committee members agreed to adopt the term “rhinosinusitis” and reached consensus on definitions and strategies for clinical research on acute presumed bacterial rhinosinusitis, chronic rhinosinusitis without polyposis, chronic rhinosinusitis with polyposis, and classic allergic fungal rhinosinusitis. Symptom and objective criteria, measures for monitoring research progress, and use of symptom scoring tools, quality-of-life instruments, radiologic studies, and rhinoscopic assessment were outlined for each condition. The recommendations from this conference should improve accuracy of clinical diagnosis and serve as a starting point for design of rhinosinusitis clinical trials.
登录
查看更多内容
影响因子：
1.1
作者：
Belden, CJ;Zinreich, SJ
通讯作者：
Zinreich, SJ
影响因子：
14.2
作者：
Bachert, C;Wagenmann, M;Rudack, C
通讯作者：
Rudack, C
影响因子：
14.2
作者：
Bachert, C;Gevaert, P;van Cauwenberge, P
通讯作者：
van Cauwenberge, P
影响因子：
3.3
作者：
Baroody, FM;Gungor, A;Naclerio, RM
通讯作者：
Naclerio, RM
影响因子：
5.9
作者：
Adkins, TN;Goodgold, HM;Slavin, RG
通讯作者：
Slavin, RG