Pyrethroid exposure among children residing in green versus non-green multi-family, low-income housing.
Pyrethroid exposure among children residing in green versus non-green multi-family, low-income housing.
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DOI：
10.1038/s41370-021-00312-w
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发表时间：
2021-05
影响因子：
4.5
通讯作者：
Chew GL
中科院分区：
文献类型：
--
作者：
Werthmann DW;Rabito FA;Stout DM 2nd;Tulve NS;Adamkiewicz G;Calafat AM;Ospina M;Chew GL
人们越来越关注儿童长期接触低剂量农药及其对健康的影响。绿色建筑实践（例如减少结构周围的热压屏障的泄漏，综合虫害管理，改善通风）有可能减少农药暴露。然而，生活在绿色住房中对儿童农药暴露的潜在影响尚不清楚。为了解决这个问题，我们对来自路易斯安那州新奥尔良市居住在绿色和非绿色住房中的68名儿童进行了一项清晨空尿中拟除虫菊酯代谢物（3-苯氧苯甲酸[3-PBA]、4-氟-3-苯氧苯甲酸[4-F-3-PBA]、反式-3-（2,2-二氯乙烯基）-2,2-二甲基环丙烷羧酸[反式dcca]）的纵向研究。研究人员对这些儿童进行了为期一年的三次农药暴露监测。广义估计方程检验了住房类型（绿色vs非绿色）和尿液拟除虫菊酯代谢物浓度之间的关系，调整了人口统计学和家庭因素。95%的样品可检出3-PBA浓度（检出限：0.1 μg/L）；4-F-3-PBA 8% (LOD: 0.1 μg/L), trans-DCCA 12% （LOD: 0.6 μg/L）。在调整后的模型中，与非绿色住房相比，绿色住房与儿童3-PBA尿浓度的统计学显著差异无关。在这项研究中，绿色建筑实践对儿童的拟除虫菊酯尿浓度没有影响。需要更大样本量的进一步研究来证实这些发现。
There is growing concern about children’s chronic low-level pesticide exposure and its impact on health. Green building practices (e.g. reducing leakage of the thermal and pressure barrier that surrounds the structure, integrated pest management, improved ventilation) have the potential to reduce pesticide exposure. However, the potential impact of living in green housing on children’s pesticide exposure is unknown. To address this question, a longitudinal study of pyrethroid metabolites (3-phenoxybenzoic acid [3-PBA], 4-fluoro-3-phenoxybenzoic acid [4-F-3-PBA], trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acid [trans-DCCA]) in first morning void urine, collected from 68 children from New Orleans, Louisiana residing in green and non-green housing was conducted. Children were followed for one year with three repeated measures of pesticide exposure. Generalized Estimating Equations examined associations between housing type (green v non-green) and urinary pyrethroid metabolite concentrations adjusting for demographic and household factors over the year. Ninety-five percent of samples had detectable concentrations of 3-PBA (limit of detection [LOD]: 0.1 μg/L); 8% of 4-F-3-PBA (LOD: 0.1 μg/L), and 12% of trans-DCCA (LOD: 0.6 μg/L). In adjusted models, green housing was not associated with statistically significant differences in children’s 3-PBA urinary concentrations compared to non-green housing. In this study, green building practices had no impact on children’s pyrethroid urinary concentrations. Further studies with larger sample sizes are needed to confirm these findings.
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从某些美国EPA儿童观察暴露研究中回顾农药尿生物标志物测量。
DOI：
10.3390/ijerph8051727
发表时间：
2011-05
影响因子：
--
作者：
Egeghy PP;Cohen Hubal EA;Tulve NS;Melnyk LJ;Morgan MK;Fortmann RC;Sheldon LS
通讯作者：
Sheldon LS
影响因子：
10.4
作者：
Barr DB;Olsson AO;Wong LY;Udunka S;Baker SE;Whitehead RD;Magsumbol MS;Williams BL;Needham LL
通讯作者：
Needham LL
影响因子：
10.4
作者：
Frumkin H;Bratman GN;Breslow SJ;Cochran B;Kahn PH Jr;Lawler JJ;Levin PS;Tandon PS;Varanasi U;Wolf KL;Wood SA
通讯作者：
Wood SA
影响因子：
12.7
作者：
Colton, Meryl D.;Laurent, Jose Guillermo Cedeno;Adamkiewicz, Gary
通讯作者：
Adamkiewicz, Gary
DOI：
10.3390/ijerph8051402
发表时间：
2011-05
影响因子：
--
作者：
Damalas CA;Eleftherohorinos IG
通讯作者：
Eleftherohorinos IG