Assessment of revascularization impact on microvascular oxygenation and perfusion using spatial frequency domain imaging.
Assessment of revascularization impact on microvascular oxygenation and perfusion using spatial frequency domain imaging.
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利用空间频域成像评估血管再造对微血管氧合和灌注的影响。
DOI：
10.1093/jscr/rjad382
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发表时间：
2023-07
影响因子：
0.5
通讯作者：
中科院分区：
文献类型：
--
作者：
微血管（直径<100 μm）在下肢组织氧合、灌注和伤口愈合中起着至关重要的作用。虽然这具有临床意义，但肢体微血管评价不是标准实践。外科干预的重点是重建受外周动脉疾病（PAD）影响的较大血管中的血流。然而，在严重微血管疾病（MVD）中，血运重建对组织氧合和灌注的影响仍然未知。我们提出的情况下，两名患者谁接受了手术血运重建外周血流量不同的结果。患者A患有PAD，而B患有PAD、重度MVD和未愈合伤口。尽管两组均显示术后踝臂指数改善，但B组的空间频域成像指标（测量微血管氧合和灌注）保持不变，表明在使用踝臂指数评估MVD的手术疗效方面存在潜在差距，并强调微循环评价以优化伤口愈合结局。
The microvasculature (with vessels <100 μm in diameter) plays a crucial role in tissue oxygenation, perfusion and wound healing in the lower limb. While this holds clinical significance, microvasculature evaluation in the limbs is not a standard practice. Surgical interventions focus on reestablishing blood flow in larger vessels affected by the peripheral artery disease (PAD). Nevertheless, the impact of revascularization on tissue oxygenation and perfusion in severe microvascular disease (MVD) is still unknown. We present the cases of two patients who underwent surgical revascularization for peripheral blood flow with different outcomes. Patient A had PAD, while B had PAD, severe MVD and a non-healing wound. Although both showed improvements in ankle-brachial index post-op, spatial frequency domain imaging metrics (which measure microvascular oxygenation and perfusion) remained unchanged in B, indicating a potential gap in assessing the surgical efficacy in MVD using ankle brachial index and emphasizing microcirculation evaluation in optimizing wound healing outcomes.
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影响因子：
4.3
作者：
Weinkauf, Craig;Mazhar, Amaan;Armstrong, David G.
通讯作者：
Armstrong, David G.
影响因子：
--
作者：
Shimazaki, Masaru;Matsuki, Takayuki;Nakamura, Yuichi
通讯作者：
Nakamura, Yuichi
影响因子：
3.5
作者：
FLYNN, MD;TOOKE, JE
通讯作者：
TOOKE, JE
视神经脊髓炎谱系疾病：妊娠相关发作和预测危险因素
DOI：
10.1136/jnnp-2020-323982
发表时间：
2020-11-20
期刊：
Journal of neurology, neurosurgery, and psychiatry
影响因子：
--
作者：
Wang L;Zhou L;ZhangBao J;Huang W;Chang X;Lu C;Wang M;Li W;Xia J;Li X;Chen L;Qiu W;Lu J;Zhao C;Quan C
通讯作者：
Quan C
影响因子：
3
作者：
Lee, Suzette;Mey, Leann;Yu, Kalvin
通讯作者：
Yu, Kalvin