Converting poorly soluble materials into stable aqueous nanocolloids.
Converting poorly soluble materials into stable aqueous nanocolloids.
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DOI:
10.1021/la1041635
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发表时间:
2011-02-01
期刊:
影响因子:
--
通讯作者:
Torchilin V
中科院分区:
文献类型:
--
作者:
Lvov YM;Pattekari P;Zhang X;Torchilin V
Aqueous nanocolloids of poorly soluble materials were produced via sonicated layer-by-layer (LbL) encapsulation with polycation / polyanion shells. Synergy of simultaneous breaking powder particles with ultrasonication and coating them with polycations allowed for the production of 150−200 nm diameter polyelectrolyte coated nanoparticles with sufficient surface electrical potential for colloidal stability. This technique increases water dispersibility of low soluble materials ranging from anticancer drugs to anticorrosion agents, dyes and inorganic salts.
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