The role of normal nasal morphological variations from race and gender differences on respiratory physiology.
The role of normal nasal morphological variations from race and gender differences on respiratory physiology.
复制标题
DOI：
10.1016/j.resp.2021.103823
复制
发表时间：
2022-03
影响因子：
2.3
通讯作者：
Frank-Ito, Dennis Onyeka
中科院分区：
文献类型：
--
作者：
Shah, Reanna;Frank-Ito, Dennis Onyeka
本研究确定了由于种族间和种族内差异和性别的鼻腔形态变化而引起的解剖学和气流诱导的关系。根据16名受试者的计算机断层扫描图像创建受试者特异性鼻气道重建：每个种族4名受试者（黑人、东亚人、高加索人和拉丁人），包括2男2女。通过计算流体动力学模拟计算鼻腔气道内的体积、表面积和鼻腔指数，以及气流速率和鼻腔阻力。结果男性鼻空域表面积（p=0.0499）和容积（p=0.0281）均显著大于女性。东亚人鼻容积最大（Median=20.38cm3， IQR= 4.58cm3），拉丁美洲人鼻表面积最大（Median=219.70cm2， IQR=29.56cm2）。平均而言，东亚和黑人女性的鼻指数比男性大。白种人鼻阻力中位数最高（0.050Pa）。s / ml,差= 0.025 horsham /毫升)。结果表明，存在不同种族和性别的解剖变异。然而，这些变异可能不会显著影响鼻功能。
This study identifies anatomical and airflow-induced relationships based on nasal morphological variations due to inter- and intra-racial differences and gender. Subject-specific nasal airway reconstruction was created from computed tomography images in 16 subjects: 4 subjects from each ethnic group (Black, East Asian, Caucasian, and Latino) comprising of 2 males and 2 females. Volume, surface area and nasal index were calculated, as well as airflow rate and nasal resistance after computational fluid dynamics simulations in the nasal airway. Results showed that nasal airspace surface area (p=0.0499) and volume (p=0.0281) were significantly greater in males than in females. Nasal volume was greatest in East Asians (Median=20.38cm3, Interquartile Range [IQR]=4.58cm3), Latinos had the greatest surface area (Median=219.70cm2, IQR=29.56cm2). On average, East Asian and Black females had larger nasal index than their male counterparts. Caucasians had the highest median nasal resistance (0.050Pa.s/ml, IQR=0.025Pa.s/ml). Results indicate that there exist anatomical variabilities based on race and gender. However, these variabilities may not significantly influence nasal function.
登录
查看更多内容
DOI：
10.1183/20734735.000318
发表时间：
2018-06
期刊：
Breathe (Sheffield, England)
影响因子：
--
作者：
LoMauro A;Aliverti A
通讯作者：
Aliverti A
影响因子：
3.4
作者：
Gungor, A;Moinuddin, R;Corey, JP
通讯作者：
Corey, JP
DOI：
10.3166/bmsap-2018-0011
发表时间：
2019-04-01
影响因子：
--
作者：
Heuze, Y.
通讯作者：
Heuze, Y.
DOI：
10.1089/jamp.2014.1205
发表时间：
2016-04-01
影响因子：
3.4
作者：
Keeler, Jarrod A.;Patki, Aniruddha;Frank-Ito, Dennis O.
通讯作者：
Frank-Ito, Dennis O.
DOI：
10.1164/ajrccm/146.6.1394
发表时间：
1992-12-01
期刊：
AMERICAN REVIEW OF RESPIRATORY DISEASE
影响因子：
--
作者：
BROOKS, LJ;STROHL, KP
通讯作者：
STROHL, KP