DNA stability: a central design consideration for DNA data storage systems.

DNA stability: a central design consideration for DNA data storage systems.
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DNA稳定性:DNA数据存储系统的核心设计考虑因素。

DOI:
10.1038/s41467-021-21587-5
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发表时间:
2021-03-01
影响因子:
16.6
通讯作者:
Keung AJ
Keung AJ
中科院分区:
综合性期刊1区
文献类型:
--
作者:
Matange K;Tuck JM;Keung AJ

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DNA中的数据存储是一项快速发展的技术,可以成为现代信息存储不断增长的能源,材料和空间需求的变革性解决方案。鉴于信息介质是DNA本身,其在不同存储和处理条件下的稳定性将从根本上影响和限制设计考虑和数据系统能力。在这里,我们分析的存储条件,分子机制,和稳定化策略影响DNA的稳定性,并提出具体的设计配置和方案,为未来的系统,最好地利用DNA存储的相当大的优势。DNA具有存储大量数据的潜力,但它会受到物理衰变的影响。在这一观点中,作者提出DNA的稳定性应该是如何将其用于数据存储的关键考虑因素。
Data storage in DNA is a rapidly evolving technology that could be a transformative solution for the rising energy, materials, and space needs of modern information storage. Given that the information medium is DNA itself, its stability under different storage and processing conditions will fundamentally impact and constrain design considerations and data system capabilities. Here we analyze the storage conditions, molecular mechanisms, and stabilization strategies influencing DNA stability and pose specific design configurations and scenarios for future systems that best leverage the considerable advantages of DNA storage. DNA has the potential to store vast amounts of data but it is subject to physical decay. In this Perspective, the authors propose that the stability of DNA should be a key consideration in how it is used for data storage.
DOI: 10.1089/bio.2013.0082
发表时间: 2014-06-01
影响因子: 1.6
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