The development of autism spectrum disorders: variability and causal complexity.
The development of autism spectrum disorders: variability and causal complexity.
复制标题
自闭症谱系障碍的发展:变异性和因果复杂性。
DOI:
10.1002/wcs.1426
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发表时间:
2017
期刊:
影响因子:
--
通讯作者:
Iverson,JanaM
中科院分区:
文献类型:
--
作者:
Wozniak,RobertH;Leezenbaum,NinaB;Northrup,JessieB;West,KelseyL;Iverson,JanaM
The autism spectrum is highly variable, both behaviorally and neurodevelopmentally. Broadly speaking, four related factors contribute to this variability: (1) genetic processes, (2) environmental events, (3) gene × environment interactions, and (4) developmental factors. Given the complexity of the relevant processes, it appears unlikely that autism spectrum atypicalities can be attributed to any one causal mechanism. Rather, the development of neural atypicality reflects an interaction of genetic and environmental risk factors. As the individual grows, changes in neural atypicality, consequent variation in behavior, and environmental response to that behavior may become linked in a positive feedback loop that amplifies deviations from the typical developmental pattern.WIREs Cogn Sci2017, 8:e1426. doi: 10.1002/wcs.1426This article is categorized under:Neuroscience > Clinical NeuroscienceNeuroscience > Development
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DOI:
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期刊:
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DOI:
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发表时间:
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The American journal of psychiatry
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