Recent updates on incubation of drug craving: a mini-review.

Recent updates on incubation of drug craving: a mini-review.
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DOI:
10.1111/adb.12205
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发表时间:
2015-09
期刊:
影响因子:
3.4
通讯作者:
Marchant NJ
Marchant NJ
中科院分区:
医学2区
文献类型:
--
作者:
Li X;Caprioli D;Marchant NJ

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在实验室动物中,在长时间从药物自我给药中撤出后,线索诱导的药物渴望逐渐增加,这种行为现象被称为“药物渴望的潜伏期”。多年来的研究已经揭示了几个重要的神经机制有助于孵化的药物渴望。在这篇简短的综述中,我们首先讨论了三篇关于人类和实验室动物对药物渴望的孵化的优秀成瘾生物学出版物。然后,我们回顾了过去一年中与药物渴望孵化相关的行为和机制发现的几个关键出版物。
Cue-induced drug craving progressively increases after prolonged withdrawal from drug self-administration in laboratory animals, a behavioral phenomenon termed “incubation of drug craving.” Studies over the years have revealed several important neural mechanisms contributing to incubation of drug craving. In this mini-review, we first discuss three excellent Addiction Biology publications on incubation of drug craving in both human and laboratory animals. We then review several key publications from the past year on behavioral and mechanistic findings related to incubation of drug craving.
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