Cognition in older women: the importance of daytime movement.
Cognition in older women: the importance of daytime movement.
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DOI：
10.1111/j.1532-5415.2008.01841.x
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发表时间：
2008-09
影响因子：
6.3
通讯作者：
Study of Osteoporotic Fractures
中科院分区：
文献类型：
--
作者：
Barnes DE;Blackwell T;Stone KL;Goldman SE;Hillier T;Yaffe K;Study of Osteoporotic Fractures
确定对80多岁的女性进行日间运动的客观测量是否与更好的认知功能相关。对2,736名没有痴呆症证据的老年妇女进行的横断面研究参与了一项健康与老龄化研究。白天的运动是用活动记录仪（一种类似手表的设备，可以客观地量化加速度计的运动）评估的，平均时间为3.0 ± 0.8天。认知功能通过线索制作测试，部分B（线索B）和简易精神状态检查（MMSE）测量。认知障碍被定义为在给定测试中比平均值差> 1.5个标准差（SD）。女性的平均年龄为83 ± 4岁; 10%为非洲裔美国人。在对年龄、种族和教育进行调整后，运动水平最高和最低四分位数的女性在认知测试中的平均得分更高（路径B快20秒[0.3 SD]，MMSE高0.3 [0.2 SD]分，均p<0.001），并且认知受损的可能性较小（比值比[95%置信区间]：试验B为0.61 [0.41 - 0.92]，MMSE为0.68 [0.44 - 1.07]）。在不同的亚组中，相关性是相似的，并且独立于自我报告的步行、医学合并症、身体功能和其他健康行为。在80多岁的女性中，使用体动记录仪客观测量的日间运动与更好的认知功能和更低的认知障碍几率相关。需要进一步的研究来阐明这种关联的方向并探索潜在的机制。
To determine whether an objective measure of daytime movement is associated with better cognitive function in women in their 80s. Cross-sectional study of 2,736 older women without evidence of dementia participating in a study of health and aging. Daytime movement was assessed with actigraphy—a watch-like device that objectively quantifies accelerometer motion—over a mean of 3.0 ± 0.8 days. Cognitive function was measured by the Trail-Making Test, Part B (Trails B) and the Mini-Mental State Examination (MMSE). Cognitive impairment was defined as performing > 1.5 standard deviations (SD) worse than the mean on a given test. Women had a mean age of 83 ± 4 years; 10% were African American. After adjustment for age, race and education, women in the highest versus lowest movement quartiles had better mean cognitive test scores (20 seconds [0.3 SD] faster on Trails B and 0.3 [0.2 SD] points higher on MMSE, both p<0.001) and were less likely to be cognitively impaired (Odds Ratio [95% Confidence Interval]: 0.61 [0.41 to 0.92] for Trails B and 0.68 [0.44 to 1.07] for MMSE). Associations were similar in different subgroups and were independent of self-reported walking, medical comorbidities, physical function and other healthy behaviors. Daytime movement as measured objectively using actigraphy was associated with better cognitive function and lower odds of cognitive impairment in women in their 80s. Additional studies are needed to clarify the direction of the association and to explore potential mechanisms.
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影响因子：
1.9
作者：
Müller, U;Czymmek, J;Von Cramon, DY
通讯作者：
Von Cramon, DY
影响因子：
--
作者：
Laurin, D;Verreault, R;Rockwood, K
通讯作者：
Rockwood, K
DOI：
10.1093/geronb/58.5.p249
发表时间：
2003-09-01
影响因子：
6.2
作者：
Crowe, M;Andel, R;Gatz, M
通讯作者：
Gatz, M
影响因子：
120.7
作者：
Abbott, RD;White, LR;Petrovitch, H
通讯作者：
Petrovitch, H
影响因子：
3.7
作者：
CLEVELAND, WS;DEVLIN, SJ
通讯作者：
DEVLIN, SJ