The role of rhythmic neural synchronization in rest and task conditions.

The role of rhythmic neural synchronization in rest and task conditions.
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DOI:
10.3389/fnhum.2011.00004
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发表时间:
2011
影响因子:
2.9
通讯作者:
Hugues E
Hugues E
中科院分区:
医学3区
文献类型:
--
作者:
Deco G;Buehlmann A;Masquelier T;Hugues E

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在许多不同的任务甚至休息时,整个大脑都存在节律性神经同步。除了它们的基本机制之外,它们的作用问题仍然存在争议。建模可以帮助我们深入了解这个难题。我们在这里回顾一下我们最近在不同情况下关于这个问题的建模结果。在休息期间,我们展示了局部节律同步如何在大脑水平上诱导时空组织的自发活动。然后,我们展示了节奏同步如何减少注意力的反应时间并增强不同神经元组之间信息传递的强度和速度。最后,我们表明,当节奏同步创建放电阶段时,重复呈现的输入模式的尖峰时间依赖性可塑性的学习大大增强。
Rhythmic neural synchronization is found throughout the brain during many different tasks and even at rest. Beyond their underlying mechanisms, the question of their role is still controversial. Modeling can bring insight on this difficult question. We review here our recent modeling results concerning this issue in different situations. During rest, we show how local rhythmic synchrony can induce a spatiotemporally organized spontaneous activity at the brain level. Then, we show how rhythmic synchrony decreases reaction time in attention and enhances the strength and speed of information transfer between different groups of neurons. Finally, we show that when rhythmic synchrony creates firing phases, the learning with spike timing-dependent plasticity of repeatedly presented input patterns is greatly enhanced.
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