Babesia and its hosts: adaptation to long-lasting interactions as a way to achieve efficient transmission.
Babesia and its hosts: adaptation to long-lasting interactions as a way to achieve efficient transmission.
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DOI：
10.1051/vetres/2009020
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发表时间：
2009-03
影响因子：
4.4
通讯作者：
Malandrin L
中科院分区：
文献类型：
--
作者：
Chauvin A;Moreau E;Bonnet S;Plantard O;Malandrin L
巴贝虫病的病原体巴贝虫是蜱传顶复门原虫。真巴贝虫（狭义巴贝虫属）的生物学特征是在红细胞中直接发育，并在蜱中经卵传播。在各种脊椎动物和蜱类宿主中描述了大量的真巴贝虫种。本文介绍了该属，然后讨论了Babelus spp的具体适应。以实现高效的传播。主要的适应性导致持久的相互作用，从而导致两个水库的诱导：在脊椎动物宿主在低长期寄生虫血症和整个生命周期的蜱虫宿主作为跨卵和transstadial传输的结果。脊椎动物宿主中这些适应的分子基础是部分已知的，但很少有蜱-宿主相互作用机制已被阐明。
Babesia, the causal agent of babesiosis, are tick-borne apicomplexan protozoa. True babesiae (Babesia genus sensu stricto) are biologically characterized by direct development in erythrocytes and by transovarial transmission in the tick. A large number of true Babesia species have been described in various vertebrate and tick hosts. This review presents the genus then discusses specific adaptations of Babesia spp. to their hosts to achieve efficient transmission. The main adaptations lead to long-lasting interactions which result in the induction of two reservoirs: in the vertebrate host during low long-term parasitemia and throughout the life cycle of the tick host as a result of transovarial and transstadial transmission. The molecular bases of these adaptations in vertebrate hosts are partially known but few of the tick-host interaction mechanisms have been elucidated.
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影响因子：
2.6
作者：
Allred, David R.;Al-Khedery, Basima
通讯作者：
Al-Khedery, Basima
影响因子：
2.6
作者：
Allred, DR
通讯作者：
Allred, DR
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作者：
Brown, Wendy C.;Norimine, Junzo;Goff, Will L.
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Goff, Will L.
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作者：
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影响因子：
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作者：
Brown, WC;Estes, DM;Suarez, CE
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Suarez, CE