RCSB Protein Data Bank: powerful new tools for exploring 3D structures of biological macromolecules for basic and applied research and education in fundamental biology, biomedicine, biotechnology, bioengineering and energy sciences.
RCSB Protein Data Bank: powerful new tools for exploring 3D structures of biological macromolecules for basic and applied research and education in fundamental biology, biomedicine, biotechnology, bioengineering and energy sciences.
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DOI：
10.1093/nar/gkaa1038
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发表时间：
2021-01-08
影响因子：
14.9
通讯作者：
Zhuravleva M
中科院分区：
文献类型：
--
作者：
Burley SK;Bhikadiya C;Bi C;Bittrich S;Chen L;Crichlow GV;Christie CH;Dalenberg K;Di Costanzo L;Duarte JM;Dutta S;Feng Z;Ganesan S;Goodsell DS;Ghosh S;Green RK;Guranović V;Guzenko D;Hudson BP;Lawson CL;Liang Y;Lowe R;Namkoong H;Peisach E;Persikova I;Randle C;Rose A;Rose Y;Sali A;Segura J;Sekharan M;Shao C;Tao YP;Voigt M;Westbrook JD;Young JY;Zardecki C;Zhuravleva M
结构生物信息学蛋白质数据库研究协作实验室(RCSB PDB)是美国结构生物信息学蛋白质数据库存档的数据中心，也是世界蛋白质数据库合作伙伴关系的创始成员之一，为美洲和大洋洲数以万计的数据储存者提供服务，并使全球数百万RCSB.org用户免费且不受限制地获得3D大分子结构数据，其中包括使用PDB101.RCSB.org的660,000名教育工作者、学生和好奇的公众。PDB数据储存者包括使用大分子结晶学、核磁共振光谱、3D电子显微镜和微电子衍射的结构生物学家。访问我们门户网站的PDB数据消费者包括研究人员、教育工作者和学习基础生物学、生物医学、生物技术、生物工程和能源科学的学生。在过去的两年中，以研究为重点的RCSB PDB门户网站(RCSB.org)经历了彻底的重新设计，利用完整的布尔运算符逻辑实现了改进的搜索，并更方便地访问与>；40外部生物数据资源集成的PDB数据。通过展示最近发布的与理解和应对新冠肺炎全球大流行相关的SARS-CoV-2蛋白质和宿主细胞蛋白质的结构的例子，详细描述了新的特征和资源。
The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB), the US data center for the global PDB archive and a founding member of the Worldwide Protein Data Bank partnership, serves tens of thousands of data depositors in the Americas and Oceania and makes 3D macromolecular structure data available at no charge and without restrictions to millions of RCSB.org users around the world, including >660 000 educators, students and members of the curious public using PDB101.RCSB.org. PDB data depositors include structural biologists using macromolecular crystallography, nuclear magnetic resonance spectroscopy, 3D electron microscopy and micro-electron diffraction. PDB data consumers accessing our web portals include researchers, educators and students studying fundamental biology, biomedicine, biotechnology, bioengineering and energy sciences. During the past 2 years, the research-focused RCSB PDB web portal (RCSB.org) has undergone a complete redesign, enabling improved searching with full Boolean operator logic and more facile access to PDB data integrated with >40 external biodata resources. New features and resources are described in detail using examples that showcase recently released structures of SARS-CoV-2 proteins and host cell proteins relevant to understanding and addressing the COVID-19 global pandemic.
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影响因子：
14.9
作者：
wwPDB consortium
通讯作者：
wwPDB consortium
影响因子：
14.9
作者：
The Gene Ontology Consortium
通讯作者：
The Gene Ontology Consortium
影响因子：
14.9
作者：
Nguyen DT;Mathias S;Bologa C;Brunak S;Fernandez N;Gaulton A;Hersey A;Holmes J;Jensen LJ;Karlsson A;Liu G;Ma'ayan A;Mandava G;Mani S;Mehta S;Overington J;Patel J;Rouillard AD;Schürer S;Sheils T;Simeonov A;Sklar LA;Southall N;Ursu O;Vidovic D;Waller A;Yang J;Jadhav A;Oprea TI;Guha R
通讯作者：
Guha R
影响因子：
1.8
作者：
Gardner, Adam;Autin, Ludovic;Goodsell, David S.
通讯作者：
Goodsell, David S.
影响因子：
14.9
作者：
Dawson NL;Lewis TE;Das S;Lees JG;Lee D;Ashford P;Orengo CA;Sillitoe I
通讯作者：
Sillitoe I