Prevalence and risk factors of primary sarcopenia in community-dwelling outpatient elderly: a cross-sectional study.

Prevalence and risk factors of primary sarcopenia in community-dwelling outpatient elderly: a cross-sectional study.
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DOI:
10.1038/s41598-020-75250-y
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发表时间:
2020-11-11
期刊:
影响因子:
4.6
通讯作者:
Lakananurak N
Lakananurak N
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Therakomen V;Petchlorlian A;Lakananurak N

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以前没有研究调查门诊原发性肌肉减少症的患病率和危险因素。本研究旨在评估门诊老年人原发性肌肉减少症的患病率及相关因素。此外,我们根据2014年和2019年亚洲肌肉减少症工作组(AWGS)标准比较了肌肉减少症的严重程度。这项横断面研究是在330名年龄超过60岁的受试者中进行的。分别使用手持式测力计、6 m步态速度和生物电阻抗分析评估肌肉力量、肌肉性能和肌肉质量。根据2014年和2019年AWGS标准,肌肉减少症的患病率为10%。肌肉减少症的发生与年龄呈正相关,中老年组(70-79岁)的比值比(OR)为6.87 [95%置信区间(CI)1.63-28.88],极老年组(≥ 80岁)为13.71(95%CI 3.66-51.41; p = 0.009)。体质虚弱和低体力活动与肌肉减少症显著相关,体质虚弱组OR为4.75(95%CI 1.90-11.89),中等体力活动组OR为15.35(95%CI 1.69-139.47),最低体力活动组OR为17.99(95%CI 1.95-165.73)。总之,原发性肌肉减少症被发现在十分之一的门诊老年人。年龄、体质虚弱、活动量少是肌少症的独立相关因素。
No previous study has investigated the prevalence and risk factors for primary sarcopenia in outpatient setting. This study aims to evaluate the prevalence and factors associated with primary sarcopenia in outpatient elderly. Additionally, we compared the severity of sarcopenia based on the 2014 and 2019 Asian Working Group for Sarcopenia (AWGS) criteria. This cross-sectional study was performed in 330 subjects aged over 60 years in an outpatient setting. The muscle strength, muscle performance and muscle mass were assessed using the handheld dynamometer, 6-m gait speed, and bioelectrical impedance analysis, respectively. The prevalence of sarcopenia was 10% as per the 2014 and 2019 AWGS criteria. The development of sarcopenia was positively correlated with the age with an odds ratio (OR) of 6.87 [95% confidence interval (CI) 1.63–28.88] in the middle-old group (70–79 years), and 13.71 (95%CI 3.66–51.41; p = 0.009) in the very old group (≥ 80 years). Prefrailty and low physical activity were significantly associated with sarcopenia with an OR of 4.75 (95%CI 1.90—11.89) in prefrailty, 15.35 (95%CI 1.69–139.47) in the middle activity group, and 17.99 (95%CI 1.95–165.73) in the lowest activity group. In conclusion, primary sarcopenia was found in one-tenth of outpatient elderly. Age, prefrailty, and low activity were independent factors associated with sarcopenia.
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发表时间: 2013-05
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