Sedentary Patterns Are Associated with Bone Mineral Density and Physical Function in Older Adults: Cross-Sectional and Prospective Data.

Sedentary Patterns Are Associated with Bone Mineral Density and Physical Function in Older Adults: Cross-Sectional and Prospective Data.
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DOI:
10.3390/ijerph17218198
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发表时间:
2020-11-06
影响因子:
--
通讯作者:
Dos Santos VR
Dos Santos VR
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Gobbo LA;Júdice PB;Hetherington-Rauth M;Sardinha LB;Dos Santos VR

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衰老会导致一些不利的形态和功能变化,如骨密度(BMD)和身体功能的下降。中等到剧烈的体力活动(MVPA)和久坐时间似乎与这些变化有关,但不同模式的影响尚不清楚。这项研究的目的是横断面和前瞻性地评估客观测量的MVPA和久坐模式(发作和休息)与老年人骨密度和身体功能之间的关系。这项研究考虑了151名巴西人(年龄60岁),其中68名参与者完成了为期两年的跟踪测量。通过加速度法测量MVPA和坐位模式,双能X线吸收法(DXA)测量骨密度(BMD)(股骨和腰椎(L1-L4)的全长),物理测试测量身体功能。在老年女性中,久坐60分钟与握力呈负相关(β=−2.03,95%CI:从−3.43到−0.63)。前瞻性分析显示,久坐运动的变化(20-30分钟和>腰椎骨密度(β=−0.0 1,95%CI:从−0.0 1至−0.0 0;β=−0.0 3,95%CI:从−0.0 6至−0.0 1)和腰椎T评分(β=−0.0 6,95%CI:从−0.10至−0.0 1;β=−0.2 7,95%CI:从−0.49至−0.0 4)与腰椎骨密度变化呈负相关。在老年女性中,久坐模式与握力有关,并且与独立于MVPA的骨密度相关。
Aging causes some unfavorable morphological and functional changes, such as the decline in bone mineral density (BMD) and physical function. Moderate-to-vigorous physical activity (MVPA) and sedentary time seem to be related with these alterations, but the impact of distinct patterns remains unclear. The aim of this study was to cross-sectionally and prospectively assess the association between objectively measured MVPA and sedentary patterns (bouts and breaks) with BMD and physical function in older adults. The study considered 151 Brazilians (aged ≥ 60 years), out of which 68 participants completed 2-year follow-up measurements. MVPA and sedentary patterns were measured by means of accelerometry, BMD—(total proximal femur and lumbar spine (L1-L4)) by means of dual-energy X-ray absorptiometry (DXA), and physical function—by means of physical tests. In older women, sedentary bouts >60 min were inversely associated with handgrip strength (β = −2.03, 95% CI: from −3.43 to −0.63). The prospective analyses showed that changes in sedentary bouts (20 to 30 min and >60 min) were inversely associated with changes in the lumbar spine’s BMD (β = −0.01, 95% CI: from −0.01 to −0.00 and β = −0.03, 95% CI: from −0.06 to −0.01) and the lumbar spine’s T-score (β = −0.06, 95% CI: from −0.10 to −0.01 and β = −0.27, 95% CI: from −0.49 to −0.04), respectively. In older women, sedentary patterns are cross-sectionally associated with handgrip strength and prospectively associated with BMD independent of MVPA.
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