Bifunctional Luminomagnetic Rare-Earth Nanorods for High-Contrast Bioimaging Nanoprobes.
Bifunctional Luminomagnetic Rare-Earth Nanorods for High-Contrast Bioimaging Nanoprobes.
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DOI：
10.1038/srep32401
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发表时间：
2016-09-02
影响因子：
4.6
通讯作者：
Kaipparettu BA
中科院分区：
文献类型：
--
作者：
Gupta BK;Singh S;Kumar P;Lee Y;Kedawat G;Narayanan TN;Vithayathil SA;Ge L;Zhan X;Gupta S;Martí AA;Vajtai R;Ajayan PM;Kaipparettu BA
Nanoparticles exhibiting both magnetic and luminescent properties are need of the hour for many biological applications. A single compound exhibiting this combination of properties is uncommon. Herein, we report a strategy to synthesize a bifunctional luminomagnetic Gd2−xEuxO3 (x = 0.05 to 0.5) nanorod, with a diameter of ~20 nm and length in ~0.6 μm, using hydrothermal method. Gd2O3:Eu3+ nanorods have been characterized by studying its structural, optical and magnetic properties. The advantage offered by photoluminescent imaging with Gd2O3:Eu3+ nanorods is that this ultrafine nanorod material exhibits hypersensitive intense red emission (610 nm) with good brightness (quantum yield more than 90%), which is an essential parameter for high-contrast bioimaging, especially for overcoming auto fluorescent background. The utility of luminomagnetic nanorods for biological applications in high-contrast cell imaging capability and cell toxicity to image two human breast cancer cell lines T47D and MDA-MB-231 are also evaluated. Additionally, to understand the significance of shape of the nanostructure, the photoluminescence and paramagnetic characteristic of Gd2O3:Eu3+ nanorods were compared with the spherical nanoparticles of Gd2O3:Eu3+.
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影响因子：
13.3
作者：
Gupta, Bipin Kumar;Narayanan, Tharangattu N.;Ajayan, Pulickel M.
通讯作者：
Ajayan, Pulickel M.
影响因子：
56.9
作者：
Larson, DR;Zipfel, WR;Webb, WW
通讯作者：
Webb, WW
影响因子：
3.5
作者：
Liu, Liqin;Ma, En;Chen, Xueyuan
通讯作者：
Chen, Xueyuan
影响因子：
3.8
作者：
Braydich-Stolle, L;Hussain, S;Hofmann, MC
通讯作者：
Hofmann, MC
直接观察纳米颗粒-癌细胞核相互作用。
影响因子：
17.1
作者：
Dam, Duncan Hieu M.;Lee, Jung Heon;Sisco, Patrick N.;Co, Dick T.;Zhang, Ming;Wasielewski, Michael R.;Odom, Teri W.
通讯作者：
Odom, Teri W.