Patterns of depressive disorders across 13 years and their determinants among midlife women: SWAN mental health study.
Patterns of depressive disorders across 13 years and their determinants among midlife women: SWAN mental health study.
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DOI：
10.1016/j.jad.2016.07.005
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发表时间：
2016-12
影响因子：
6.6
通讯作者：
Joffe H
中科院分区：
文献类型：
--
作者：
Bromberger JT;Kravitz HM;Youk A;Schott LL;Joffe H
人们对中年女性抑郁症的发病过程知之甚少。本研究旨在通过13年的随访，确定区分持续性或复发性抑郁症的风险因素与较温和过程的风险因素的因素。297名42-52岁的黑人和白色绝经前妇女参加了全国妇女健康研究匹兹堡网站。精神病学访谈获得了基线时终生精神病诊断和每年抑郁症发生率的信息。我们确定了四种抑郁模式：91例（31%）患有持续/复发性重度抑郁症（MDD），27例（9%）单次发作MDD，35例（12%）仅为轻度抑郁症（minD），144例（48%）无抑郁症。我们比较了持续性/复发性MDD组与其他三组的基线风险因素。持续性/复发组的女性比其他三组更有可能报告终身重度或轻度抑郁史（p值=.001-.08）和前一年2+非常令人不安的生活事件（p值=.003-.04）。持续/复发组比MinD组更有可能报告抑郁症家族史（p= 0.03），并且在基线时比单次发作MDD组报告当前睡眠问题（p= 0.002）。少数患有minD或单次发作MDD的女性。回顾性报告儿童期虐待和抑郁症家族史。持续性/复发性抑郁症在中年时期很常见。除了抑郁症的个人和家族史外，中年医疗保健提供者应该认识到，当前的睡眠问题和最近非常令人不安的事件是恶性抑郁症过程的强烈风险因素。
Little is known about the course of depression in midlife women. This study aims to identify factors that distinguish risk factors for persistent or recurrent depression from those of a milder course across 13-years of follow-up. 297 Black and White premenopausal women aged 42-52 were enrolled at the Study of Women's Health Across the Nation Pittsburgh site. Psychiatric interviews obtained information on lifetime psychiatric diagnoses at baseline and occurrences of depression annually. We identified four depression patterns: 91(31%) had Persistent/recurrent major depressive disorder (MDD), 27(9%) Single Episode MDD, 35(12%) Minor Depression (minD) only, 144(48%) No Depression. We compared baseline risk factors for the Persistent/recurrent MDD group with each of the other three. A lifetime history of major or minor depression (p-values =.001-.08) and 2+ very upsetting life events in the previous year (p-values=.003-.04) were more likely to be reported by women in the Persistent/recurrent group than in the other three. The Persistent/recurrent group was more likely to report a family history of depression (p=.03) than the MinD group, and to report current sleep problems (p=.002) at baseline than the Single Episode MDD group. Small numbers of women with minD or a Single Episode MDD. Childhood maltreatment and family depression history were retrospectively reported. A Persistent/recurrent depression course is common during midlife. In addition to personal and family histories of depression, providers of midlife health care should recognize that current sleep problems and recent very upsetting events are strong risk factors for a pernicious depression course.
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影响因子：
6.5
作者：
Baglioni, Chiara;Spiegelhalder, Kai;Nissen, Christoph;Riemann, Dieter
通讯作者：
Riemann, Dieter
影响因子：
3.2
作者：
Bromberger JT;Kravitz HM
通讯作者：
Kravitz HM
DOI：
10.1016/b978-0-08-045078-0.00014-9
发表时间：
2008-01-01
期刊：
RISK FACTORS IN DEPRESSION
影响因子：
--
作者：
Harkness, Kate L.
通讯作者：
Harkness, Kate L.
影响因子：
4.8
作者：
Bernstein, DP;Stein, JA;Zule, W
通讯作者：
Zule, W
影响因子：
6.9
作者：
Bromberger, J. T.;Schott, L.;Joffe, H.
通讯作者：
Joffe, H.