Effect of peripapillary tilt direction and magnitude on central visual field defects in primary open-angle glaucoma with high myopia

Effect of peripapillary tilt direction and magnitude on central visual field defects in primary open-angle glaucoma with high myopia
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视乳头周围倾斜方向和幅度对高度近视原发性开角型青光眼中心视野缺损的影响

DOI:
10.1007/s10384-020-00747-y
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发表时间:
2020
影响因子:
2.4
通讯作者:
Nishida Kohji
Nishida Kohji
中科院分区:
医学4区
文献类型:
--
作者:
Usui Shinichi;Ikuno Yasushi;Asai Tomoko;Kikawa Tsutomu;Akiba Masahiro;Miki Atsuya;Matsushita Kenji;Kawasaki Ryo;Nishida Kohji

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目的探讨轴性近视眼青光眼视乳头周围倾斜与视野缺陷的关系。回顾性横断面研究。10 4例(10 4只眼)伴有近视的原发性开角型青光眼(POAG)患者,其中高度近视5 2只眼,≤眼轴2 6.5 mm,眼轴30.0 mm;用光学相干断层扫描评估乳头周围倾斜的方向和大小。根据时钟小时扇区定义的倾斜方向,将眼睛分为12组,右眼为顺时针方向,左眼为逆时针方向。评价平均偏差(MD)和中心VF(CVF)值,即瑞典交互阈值算法30-2检验5度内4个旁中心点的平均阈值。倾斜方向为9区(47.1%)和8区(34.6%)。9区组的MD和CVF值明显低于8区组(P=0.013和P=0.019)。此外,在HM的POAG眼中,9区组较小的乳头周围倾斜幅度与CVF呈负相关(P=0.0019.0 1),与MD无相关性(P=0.1)。而9区组卵圆度指数与MD(P=0.4)和CVF(P=0.36)无显著相关。伴有HM的POAG眼较小的颞侧乳头周围倾斜与CVF缺陷相关。HM的POAG眼的CVF缺陷与视乳头周围倾斜方向和程度有关。
To evaluate the relationship between peripapillary tilt and visual field (VF) defects in glaucomatous eyes with axial myopia. Retrospective cross-sectional study. One hundred four eyes of 104 patients with primary open-angle glaucoma (POAG) with myopia were included (52 eyes with high myopia [HM], 26.5 mm≤ axial length [AL] 30.0 mm; and 52 eyes without HM, 24.0 mm AL 26.5 mm). The direction and magnitude of the peripapillary tilt were evaluated using optical coherence tomography. The eyes were divided into 12 groups according to the tilt directions defined by clock-hour sectors in a clockwise direction in the right eyes and in a counterclockwise direction in the left eyes. The mean deviation (MD) and central VF (CVF) values, ie, the mean threshold values of 4 paracentral points within 5 degrees of the Swedish Interactive Threshold Algorithm 30-2 test, were evaluated. The direction of the tilt was toward sector 9 (47.1%) and sector 8 (34.6%). The MD and CVF values were significantly worse (P= 0.013 and P= 0.019, respectively) in the sector 9 group than in the sector 8 group. Furthermore, the smaller peripapillary tilt magnitude in the sector 9 group was negatively correlated (P= 0.0019) with the CVF but not with the MD (P= 0.1) among the POAG eyes with HM. In contrast, the ovality index in the sector 9 group was not significantly correlated with the MD (P= 0.4) or the CVF (P= 0.36). A smaller temporal peripapillary tilt correlated with CVF defects in POAG eyes with HM. The peripapillary tilt direction and magnitude affect the CVF defect in POAG eyes with HM.
DOI: 10.1167/iovs.09-3716
发表时间: 2009-11-01
影响因子: 4.4
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期刊: OPHTHALMOLOGY
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发表时间: 2010-07-01
影响因子: 2.4
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