Miniature mass spectrometer-based point-of-care assay for measuring phosphatidylethanol in blood.
Miniature mass spectrometer-based point-of-care assay for measuring phosphatidylethanol in blood.
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DOI:
10.1039/d3an00098b
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发表时间:
2023-03-27
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--
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We demonstrate proof-of-concept for point-of-care assessment of long-term alcohol consumption by measuring phosphatidylethanol in blood/dried blood spots with nano-electrospray ionization and MS/MS using a miniature mass spectrometer. ‘Abstinence’, ‘moderate’, and ‘chronic’ consumption could be distinguished rapidly for both sample types, and quantitative performance was obtained with blood (LoQ-100 ng mL−1).
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影响因子:
2.9
作者:
Isaksson, Anders;Walther, Lisa;Alling, Christer
通讯作者:
Alling, Christer
影响因子:
2.3
作者:
Gnann, H.;Weinmann, W.;Bouzas, N. Ferreiros
通讯作者:
Bouzas, N. Ferreiros
影响因子:
7.4
作者:
Snyder DT;Pulliam CJ;Ouyang Z;Cooks RG
通讯作者:
Cooks RG
影响因子:
4.7
作者:
KOBAYASHI, M;KANFER, JN
通讯作者:
KANFER, JN
影响因子:
4.2
作者:
Huang, Guangming;Xu, Wei;Cooks, R. Graham
通讯作者:
Cooks, R. Graham