Modified STEADI Fall Risk Categories Predict Incident Cognitive Impairment.
Modified STEADI Fall Risk Categories Predict Incident Cognitive Impairment.
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DOI：
10.1111/jgs.17034
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发表时间：
2021-05
影响因子：
6.3
通讯作者：
Batsis JA
中科院分区：
文献类型：
--
作者：
Crow RS;Haudenschild C;Lohman MC;Roth RM;Roderka M;Masterson T;Brand J;Gooding T;Mackenzie TA;Batsis JA
目前尚不清楚福尔斯跌倒风险高但无认知障碍的老年人是否有更高的后续认知障碍率。这是对NHATS的横截面和纵向数据的分析。国家健康和老龄化趋势研究，2011-2019年社区居住的65岁及以上无认知障碍的成年人数据的二次分析参与者在基线时被分为三类跌倒风险使用来自疾病控制中心STEADI的改进算法，（停止老年人事故，死亡和伤害）和跌倒风险来自纵向国家健康和老龄化趋势研究（NHATS）的数据。整体认知受损定义为阿尔茨海默病-8评分、即时/延迟回忆、定向、画钟测试或日期/人物回忆中NHATS衍生的损伤。主要结局是8年随访期内首次发生认知障碍。Cox比例风险模型确定了至认知功能障碍发作的时间（参照物=低改良STEADI发生率）。在7,146名参与者（57.8%为女性）中，中位年龄为75-80岁。参与者中基线跌倒改良STEADI风险类别的患病率为低（51.6%）、中（38.5%）和高（9.9%）。在我们的完全校正模型中，中度风险类别中发生认知障碍的风险为HR 1.18 [95%CI：1.08，1.29]，高危类别中为HR 1.74 [95%CI：1.53，1.98]。在基线时具有高跌倒风险的老年认知功能完整的成年人在8年随访时认知功能下降的风险几乎是其两倍。
It is unknown whether older adults at high risk of falls but without cognitive impairment have higher rates of subsequent cognitive impairment. This was an analysis of cross-sectional and longitudinal data from NHATS. National Health and Aging Trends Study, secondary analysis of data from 2011-2019 Community dwelling adults age 65 and over without cognitive impairment Participants were classified at baseline in three categories of fall risk (low, moderate, severe) using a modified algorithm from the Center for Disease Control’s STEADI (Stop Elderly Accidents, Deaths, and Injuries) and fall risk from data from the longitudinal National Health and Aging Trends Study (NHATS). Impaired global cognition was defined as NHATS-derived impairment in either the Alzheimer’s Disease-8 score, immediate/delayed recall, orientation, clock-drawing test, or date/person recall. The primary outcome was the first incident of cognitive impairment in an 8 year follow-up period. Cox-proportional hazard models ascertained time to onset of cognitive impairment (referent = low modified STEADI incidence). Of the 7,146 participants (57.8% female), the median age category was 75-80 years. Prevalence of baseline fall modified STEADI risk categories in participants was low (51.6%), medium (38.5%) and high (9.9%). In our fully adjusted model, the risk of developing cognitive impairment was HR 1.18 [95%CI: 1.08, 1.29] in the moderate risk category, and HR 1.74 [95%CI: 1.53, 1.98] in the high-risk category. Older, cognitively intact adults at high fall risk at baseline had nearly twice the risk of cognitive decline at 8 year follow up.
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DOI：
10.1093/gerona/gly148
发表时间：
2019-05-16
期刊：
The journals of gerontology. Series A, Biological sciences and medical sciences
影响因子：
--
作者：
Montero-Odasso M;Almeida QJ;Bherer L;Burhan AM;Camicioli R;Doyon J;Fraser S;Muir-Hunter S;Li KZH;Liu-Ambrose T;McIlroy W;Middleton L;Morais JA;Sakurai R;Speechley M;Vasudev A;Beauchet O;Hausdorff JM;Rosano C;Studenski S;Verghese J;Canadian Gait and Cognition Network
通讯作者：
Canadian Gait and Cognition Network
影响因子：
--
作者：
Galvin, James E.;Roe, Catherine M.;Morris, John C.
通讯作者：
Morris, John C.
影响因子：
3
作者：
Cocchini, G;Della Sala, S;Spinnler, H
通讯作者：
Spinnler, H
DOI：
10.1046/j.1532-5415.2003.51516.x
发表时间：
2003-11-01
影响因子：
6.3
作者：
Sheridan, PL;Solomont, J;Hausdorff, JM
通讯作者：
Hausdorff, JM
影响因子：
1.7
作者：
Ciesielska, Natalia;Sokolowski, Remigiusz;Kedziora-Kornatowska, Kornelia
通讯作者：
Kedziora-Kornatowska, Kornelia