Is relational reasoning dependent on language? A voxel-based lesion symptom mapping study.
Is relational reasoning dependent on language? A voxel-based lesion symptom mapping study.
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DOI：
10.1016/j.bandl.2010.01.004
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发表时间：
2010-05
影响因子：
2.5
通讯作者：
Dronkers, Nina F.
中科院分区：
文献类型：
--
作者：
Baldo, Juliana V.;Bunge, Silvia A.;Wilson, Stephen M.;Dronkers, Nina F.
先前对脑受损的患者的研究表明，即使在当前的研究中，我们的语言能力对于复杂的问题解决也是必要的。在乌鸦的彩色渐进式矩阵（RCPM）上，中风患者（n = 107）患有一系列语言障碍。该解决方案的六个可能选择是通过视觉模式匹配来确定的，但其他项目需要更复杂的关系，如预测的那样。相对于非仇恨的左半球患者的失语是一种基于体素的病变象征（VLSM）程序，以将患者的RCPM表现与大脑的损害区域联系起来。与左中和上级临时回旋中的病变相关，语言处理所必需视觉处理，即枕骨和颞叶皮质。
Previous studies with brain-injured patients have suggested that language abilities are necessary for complex problem solving, even when tasks are non-verbal. In the current study, we tested this notion by analyzing behavioral and neuroimaging data from a large group of left-hemisphere stroke patients (n = 107) suffering from a range of language impairment from none to severe. Patients were tested on the Raven’s Colored Progressive Matrices (RCPM), a non-verbal test of reasoning that requires participants to complete a visual pattern or sequence with one of six possible choices. For some items, the solution could be determined by visual pattern-matching, but other items required more complex, relational reasoning. As predicted, performance on the relational-reasoning items was disproportionately affected in language-impaired patients with aphasia, relative to non-aphasic, left-hemisphere patients. A voxel-based lesion symptom mapping (VLSM) procedure was used to relate patients’ RCPM performance with areas of damage in the brain. Results showed that deficits on the relational reasoning problems were associated with lesions in the left middle and superior temporal gyri, regions essential for language processing, as well as in the left inferior parietal lobule. In contrast, the visual pattern-matching condition was associated with lesions in posterior portions of the left hemisphere that subserve visual processing, namely, occipital and inferotemporal cortex. These findings provide compelling support for the idea that language is critical for higher-level reasoning and problem-solving.
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影响因子：
3.7
作者：
Bunge, SA;Wendelken, C;Wagner, AD
通讯作者：
Wagner, AD
影响因子：
3.4
作者：
Dronkers, NF;Wilkins, DP;Jaeger, JJ
通讯作者：
Jaeger, JJ
影响因子：
3.2
作者：
Kimberg, Daniel Y.;Coslett, H. Branch;Schwartz, Myrna F.
通讯作者：
Schwartz, Myrna F.
影响因子：
14.5
作者：
BASSO, A;DERENZI, E;SPINNLER, H
通讯作者：
SPINNLER, H
影响因子：
14.5
作者：
BASSO, A;CAPITANI, E;SPINNLER, H
通讯作者：
SPINNLER, H