Medication-taking self-efficacy and medication adherence among HIV-infected cocaine users.

Medication-taking self-efficacy and medication adherence among HIV-infected cocaine users.
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艾滋病毒感染的可卡因使用者中服药的自我效能和药物遵守。

DOI:
10.1016/j.jana.2012.05.005
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发表时间:
2013-05
期刊:
The Journal of the Association of Nurses in AIDS Care : JANAC
影响因子:
--
通讯作者:
Ownby RL
Ownby RL
中科院分区:
其他
文献类型:
--
作者:
Waldrop-Valverde D;Dong C;Ownby RL

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这项前瞻性的观察性研究测试了服用抗逆转录病毒药物的自我效能对现任和前任可卡因和海洛因使用者服药依从性的预测能力。使用电子监视器记录瓶口开度和自我报告服药依从性的措施。样本包括99名男性和女性,他们每隔4周接受一次为期6个月的采访。用混合效应回归模型检验药物使用和服药自我效能与每次就诊时自我报告依从率、服药依从率、服药天数和服药依从性之间的关系,结果表明,服药自我效能感与除服药依从性外的所有服药依从性指标均显著相关。研究结果还显示,在研究期间,电子监控的遵从性指标有所下降,而自我报告的遵从性没有下降。研究结果表明,自我效能感可以对坚持剂量产生持续影响,但可能不是坚持正确时间的有效预测因素。
This prospective, observational study tested the ability of self-efficacy for taking antiretroviral medications to predict medication adherence among current and former cocaine and heroin users. Electronic monitors to record bottle openings and self-report measures of medication adherence were used. The sample included 99 men and women who were interviewed at 4-week intervals for 6 months. Mixed effects regression models to test the relationship of substance use and self-efficacy for medication-taking with percent of self-report adherence, dose adherence, number of days adherent, and adherence to medication schedule at each study visit showed that medication-taking self-efficacy was significantly related to all measures of adherence except schedule adherence. Findings also showed that electronically monitored adherence measures declined over the study period whereas self-report adherence did not. Findings suggest that self-efficacy can have a sustained effect on adherence to doses but may not be an influential predictor of adherence to their correct timing.
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发表时间: 2003-08-15
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影响因子: 3.8
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