Carbon nanotubes in hyperthermia therapy.

Carbon nanotubes in hyperthermia therapy.
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DOI:
10.1016/j.addr.2013.08.001
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发表时间:
2013-12
影响因子:
16.1
通讯作者:
Torti, Suzy V.
Torti, Suzy V.
中科院分区:
医学1区
文献类型:
--
作者:
Singh, Ravi;Torti, Suzy V.

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热肿瘤消融疗法正在开发各种纳米材料,包括单壁和多壁碳纳米管。碳纳米管(CNTs)由于其同时成像和治疗的潜力而引起了人们的兴趣。在这篇综述中,我们重点介绍了碳纳米管介导的热疗法(CNMTT)在体内的应用,并研究了在复发性肿瘤或对传统癌症治疗有耐药性的肿瘤中使用这种疗法的基本原理。此外,我们讨论了定位和增强这种治疗的癌症选择性的策略,并简要检查了与碳纳米管的毒性和长期命运有关的问题。
Thermal tumor ablation therapies are being developed with a variety of nanomaterials, including single-and multiwalled carbon nanotubes. Carbon nanotubes (CNTs) have attracted interest due to their potential for simultaneous imaging and therapy. In this review, we highlight in vivo applications of carbon nanotube-mediated thermal therapy (CNMTT) and examine the rationale for use of this treatment in recurrent tumors or those resistant to conventional cancer therapies. Additionally, we discuss strategies to localize and enhance the cancer selectivity of this treatment and briefly examine issues relating the toxicity and long term fate of CNTs.
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期刊: Nanomedicine (London, England)
影响因子: --
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