Cognition in males and females with autism: similarities and differences.
Cognition in males and females with autism: similarities and differences.
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患有自闭症的男性和女性的认知：相似性和差异。
DOI：
10.1371/journal.pone.0047198
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发表时间：
2012
期刊：
影响因子：
3.7
通讯作者：
Baron-Cohen S
中科院分区：
文献类型：
--
作者：
Lai MC;Lombardo MV;Ruigrok AN;Chakrabarti B;Wheelwright SJ;Auyeung B;Allison C;MRC AIMS Consortium;Baron-Cohen S
自闭症谱系障碍（ASC）中的男性偏见导致女性与ASC研究不足。这种对女性的缺乏关注可能会隐藏由于性别造成的变异性，这可能解释ASC内的一些异质性。在这项研究中，我们调查了四个关键的认知领域（心智化和情绪感知，执行功能，感知注意细节，运动功能）在ASC，测试的相似性和差异，男性和女性之间的ASC和不ASC（n = 128成人，n = 32每组）。 在心智化和面部情绪感知领域，男性和女性与ASC表现出类似的赤字相比，神经典型的控制。然而，在注意细节和灵活性，涉及执行功能，虽然男性与ASC表现出较差的性能相对于神经型男性，女性与ASC进行神经型女性。我们的结论是，在社会认知领域的表现是同样受损的男性和女性的成年人与ASC。然而，在特定的非社会认知领域，ASC内的性能取决于性别。这表明，在特定的领域，在ASC的认知概况调制的性别。
The male bias in autism spectrum conditions (ASC) has led to females with ASC being under-researched. This lack of attention to females could hide variability due to sex that may explain some of the heterogeneity within ASC. In this study we investigate four key cognitive domains (mentalizing and emotion perception, executive function, perceptual attention to detail, and motor function) in ASC, to test for similarities and differences between males and females with and without ASC (n = 128 adults; n = 32 per group). In the mentalizing and facial emotion perception domain, males and females with ASC showed similar deficits compared to neurotypical controls. However, in attention to detail and dexterity involving executive function, although males with ASC showed poorer performance relative to neurotypical males, females with ASC performed comparably to neurotypical females. We conclude that performance in the social-cognitive domain is equally impaired in male and female adults with ASC. However, in specific non-social cognitive domains, performance within ASC depends on sex. This suggests that in specific domains, cognitive profiles in ASC are modulated by sex.
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影响因子：
3.3
作者：
Burack, JA;Iarocci, G;Mottron, L
通讯作者：
Mottron, L
影响因子：
5.2
作者：
Bolte, Sven;Duketis, Eftichia;Holtmann, Martin
通讯作者：
Holtmann, Martin
影响因子：
7.6
作者：
Baron-Cohen, S;Wheelwright, S;Plumb, I
通讯作者：
Plumb, I
影响因子：
64.8
作者：
Adolphs, R;Gosselin, F;Damasio, AR
通讯作者：
Damasio, AR
DOI：
10.1097/chi.0b013e318030e28b
发表时间：
2007-04-01
影响因子：
13.3
作者：
Bloss, Cinnamon S.;Courchesne, Eric
通讯作者：
Courchesne, Eric