EMAP/EMAPA ontology of mouse developmental anatomy: 2013 update.
EMAP/EMAPA ontology of mouse developmental anatomy: 2013 update.
复制标题
小鼠发育解剖学的EMAP/EMAPA本体：2013年更新。
DOI：
10.1186/2041-1480-4-15
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发表时间：
2013-08-26
影响因子：
1.9
通讯作者：
Baldock RA
中科院分区：
文献类型：
--
作者：
Hayamizu TF;Wicks MN;Davidson DR;Burger A;Ringwald M;Baldock RA
Edinburgh Mouse Atlas Project（EMAP）小鼠发育解剖学本体提供了描述正常和突变小鼠胚胎解剖学的标准命名法。本体构成了EMAP图谱的核心，并被小鼠基因表达数据库（GXD）、爱丁堡小鼠基因表达图谱（EMAGE）和其他数据库资源用于注释基因表达数据。最初的EMAP本体分别列出了每个发育阶段的解剖实体，作为一个严格的partonomy组织的单亲图。一个“抽象的”（即非阶段特异性）表示小鼠发育解剖学已经开发出来。在该版本（EMAPA）中，给定解剖实体的所有实例都作为单个术语呈现，以及认为存在的第一个和最后一个阶段。现在使用“主要”非定时版本中的分期信息导出定时组件解剖结构。解剖实体呈现为有向非循环图，从而实现多个亲本关系。现在可以表示包含分类以及部分分类和其他类型的关系。大多数概念名称都是唯一的，复合名称使用标准化的命名惯例构建，替代名称作为同义词关联。本体已经在EMAP和GXD之间的合作努力中进行了扩展和改进，并从其他人那里获得了额外的输入。目前还在努力改进更新和编辑控制方面的修订过程。修订后的EMAPA本体可从OBO Foundry资源免费获得，相关Wiki页面（http：//www.obofoundry.org/wiki/index.php/EMAPA：Main_Page）提供了描述性信息和其他文档。
The Edinburgh Mouse Atlas Project (EMAP) ontology of mouse developmental anatomy provides a standard nomenclature for describing normal and mutant mouse embryo anatomy. The ontology forms the core of the EMAP atlas and is used for annotating gene expression data by the mouse Gene Expression Database (GXD), Edinburgh Mouse Atlas of Gene Expression (EMAGE) and other database resources. The original EMAP ontology listed anatomical entities for each developmental stage separately, presented as uniparental graphs organized as a strict partonomy. An "abstract" (i.e. non-stage-specific) representation of mouse developmental anatomy has since been developed. In this version (EMAPA) all instances for a given anatomical entity are presented as a single term, together with the first and last stage at which it is considered to be present. Timed-component anatomies are now derived using staging information in the "primary" non-timed version. Anatomical entities are presented as a directed acyclic graph enabling multiple parental relationships. Subsumption classification as well as partonomic and other types of relationships can now be represented. Most concept names are unique, with compound names constructed using standardized nomenclature conventions, and alternative names associated as synonyms. The ontology has been extended and refined in a collaborative effort between EMAP and GXD, with additional input from others. Efforts are also underway to improve the revision process with regards to updating and editorial control. The revised EMAPA ontology is freely available from the OBO Foundry resource, with descriptive information and other documentation presented in associated Wiki pages (http://www.obofoundry.org/wiki/index.php/EMAPA:Main_Page).
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影响因子：
12.3
作者：
通讯作者：
--
影响因子：
14.9
作者：
Finger JH;Smith CM;Hayamizu TF;McCright IJ;Eppig JT;Kadin JA;Richardson JE;Ringwald M
通讯作者：
Ringwald M
影响因子：
12.3
作者：
Smith CL;Goldsmith CA;Eppig JT
通讯作者：
Eppig JT
影响因子：
46.9
作者：
Smith, Barry;Ashburner, Michael;Lewis, Suzanna
通讯作者：
Lewis, Suzanna
影响因子：
12.3
作者：
Mungall CJ;Torniai C;Gkoutos GV;Lewis SE;Haendel MA
通讯作者：
Haendel MA